Historically, phosphoinositide-specific phospholipase C (PI-PLC) catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) to generate the second messengers, inositol 1,4,5-trisphosphate (InsP3) and diacylglycerol (DAG), which release Ca2+from intracellular stores and activate members of...
性质:又称二磷酸磷脂酰肌醇。系磷脂类化合物之一。磷脂酰肌醇是它的前体。左脑中含量颇多,所以通常从脑中提取。在脑膜中,由磷脂酰肌醇激酶(Ec.2.7.1.6.7.)催化其前体而成。它又是很多第二信使物质(如磷酸肌醇类)的前体,所以也是磷脂酶C(phospholipase C)的作用底物之一。产品由从牛脑中提取,并制成其铵盐冻干...
As highlighted in this review, the phosphoinositide-phospholipase C pathway is strongly implicated in the control of mouse oocyte meiosis. The pathway becomes progressively functional as oocyte growth advances, and it appears to play a role in the G2/M transition when meiosis resumes, at least in...
产品名称 Phospholipase C Beta 3, Phosphoinositide Specific (PLCb3) Polyclonal Antibody 产品货号 CAU25637 产品价格 现货询价,电话:010-67529703 产品规格 200 μg 产品品牌 bioma 产品概述 [ 其他名称:1-磷脂酰肌醇-4,5-二磷酸磷酸二酯酶β-3 免疫原:PLCb3(Asp318~Lys468) 验证反应性:小鼠(Mus ...
Mammalian phosphoinositide-specific phospholipases C (PI-PLCs) are involved in most receptor-mediated signal transduction pathways. The mammalian isozymes employ a modular arrangement of domains to achieve a regulated production of two key second messengers. The roles of the PH, EF hand, C2, SH2...
PLC (Phosphoinositide-specific phospholipase C) plays a significant role in transmembrane signaling. Four members of PLCs have been identified: PLCB,PLCg,PLCd,and PLCe. In response to extracellular stimuli (e.g.,hormone,growth factors,neurotrans
Synonyms:PLCb3 (Phospholipase C Beta 3, Phosphoinositide Specific, 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Beta-3) CAS: MF: MW:0 EINECS: Mol File:Mol File Information Error Report Your Email: Browse by provincePLCb3 (Phospholipase C Beta 3, Phosphoinositide Specific, 1-Phosphatidy...
英文名字 PLCB1, CT (PLCB1, KIAA0581, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1, PLC-154, Phosphoinositide phospholipase C-beta-1, Phospholipase C-I, Phospholipase C-beta-1)供应商 MyBioSource产品货号 MBS641332产品报价 ￥询价/0.2mL ￥询价/5x0.2mL ￥询价/其它规格产品说明...
Moreover, Dex treatment rapidly induces diacylglycerol (DAG) generation, through a protein kinase C (PKC) and G-protein–dependent phosphatidylinositol-specific phospholipase C (PI-PLC), an event which precedes and is required for aSMase activation. Indeed, PI-PLC inhibition by U73122 totally ...
inositidephosphoinositidenucleusphospholipaserevisitingtransduction Advan.EnzymeRegul.46(2006)2–11Signaltransductionwithinthenucleus:Revisitingphosphoinositideinositide–specificphospholipaseCb1LucioCoccoa,Ã,AlbertoM.Martellia,b,c,RobertaFiumea,IreneFaenzaa,AnnaMariaBillia,FrancescoAntonioManzoliaaCellularSignali...