In the polymerization of DNA, a phosphodiester bond is formed between a phosphate group of the nucleotide being added and which of the following atoms or molecules of the last nucleotide in the DNA strand? Select textbook and university Improve your experience by picki...
Understand what a phosphodiester bond is, learn about phosphodiester bond formation, explore the role of phosphodiester bonds in DNA and RNA, and discover its biological importance. Updated: 11/21/2023 Table of Contents What is a Phosphodiester Bond? Phosphodiester Bond Formation Phosphodiester Bonds...
A single-strand break (SSB) occurs when the phosphodiester bond on one DNA strand is broken, as opposed to a double-strand break (DSB) which involves both DNA strands (Fig. 2.4). SSBs are sometimes referred to as “nicks” in the DNA backbone.Graphic design credit: Angie Ambers, MA, ...
DNA sequencing experiments have shown that strand breakage occurs by the specific cleavage of the phosphodiester bond which lies immediately 3' to guanine residues in the DNA, leaving some alkali-labile remnant attached to the terminal phosphate. A mechanism for DNA strand breakage which involves the...
the 3’- and 5’- phosphodiester linkages are extremely stable even without the employment of the catalysts. Furthermore, it has been estimated that the half-life of the hydrolysis of a phosphodiester bond in DNA at room temperature is 30 million years, which elaborates that the phosphodiester...
To solve the question regarding the linkages in a DNA molecule, we will break down the components involved and identify the correct linkages step by step.Step 1: Understanding the Structure of DNA DNA (deoxyribonucleic acid) is
A nick is a break in a phosphodiester bond in one strand of a double-helix. From: Molecular Biology, 1995 About this pageSet alert Also in subject areas: Biochemistry, Genetics and Molecular Biology Nursing and Health Professions Pharmacology, Toxicology and Pharmaceutical ScienceDiscover other topic...
The condensation of the nucleotides forms DNA and RNA. The condensation occurs between the... Learn more about this topic: Phosphodiester Bond in DNA & RNA | Linkage, Formation & Function from Chapter 6/ Lesson 5 84K Understand wh...
Phosphodiester Bond in DNA & RNA | Linkage, Formation & Function from Chapter 6 / Lesson 5 84K Understand what a phosphodiester bond is, learn about phosphodiester bond formation, explore the role of phosphodiester bonds in DNA and RNA, and discover its biological importance. Related...
Tyr72 forms a water-mediated hydrogen bond with Glu143, while Tyr75/Tyr188 and Tyr157 form direct hydrogen bonds with Asp32 and Glu190, respectively, thereby stabilizing the conformation of the choline-binding pocket. In addition, Trp139 and Pro140 in the "insertion loop" (residues 139–157...