28735-1-AP targets Phospho-p70(S6K) (Thr389) in WB, IHC, ELISA applications and shows reactivity with human samples. Tested Applications WB, ELISA Application Description Cited Applications WB, IHC Tested Reactivity human Cited Reactivity human, mouse, rat Immunogen Peptide 种属同源性预测 Host ...
Phospho-P70 S6K (Thr389) Rabbit Polyclonal Antibody -20ºC保存,Western一抗稀释液-20ºC或4ºC保存,一年有效。Western一抗稀释液优先推荐4ºC保存,长期不使用可以考虑-20ºC保存,但冻融可能会导致出现轻微的浑浊和少量不溶物。 注意事项: ...
Description:Rabbit polyclonal antibody to p70 S6K (phospho-T389) Specificity:p-p70 S6K (T389) pAb detects endogenous levels of p70 S6 kinase only when phosphorylated at Thr389. This antibody also detects p85 S6 kinase when phosphorylated at Thr412. ...
Neonatal seizures transiently activate the mTORC1 downstream targets phospho-4E-BP1 (Thr37/46), phospho-p70S6K (Thr389), and phospho-S6 (Ser235/236).Delia, M. TalosHongyu, SunXiangping, ZhouErin, C. FitzgeraldMichele, C. Jackson...
This regulation results in the phosphorylation of multiple sites of p70 S6K, including Thr389 within the linker domain, which is required for full activation. Activated p70 S6K phosphorylates several residues on the S6 ribosomal protein, thereby leading to increased protein synthesis. 产品留言 标题...
应用类型 Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects p70 S6 kinase only when phosphorylated at Thr389. 免疫原 Synthetic phospho-peptide surrounding amino acid Ser389 of human p70 S6 kinase ...
Phosphorylation of Thr229 in the catalytic domain and Thr389 in the linker domain are most critical for kinase function. Stimulation of mammalian cells by a variety of mitogenic stimuli results in a rapid, biphasic activation of p70S6K. Inhibition of p70 activity inhibits the entry into S phase...