The phospho-mimic Cx43 also reduced pathological hyperdensity and transverse directionality of microtubules in mdx cardiomyocytes. Colchicine (Colch) treatment, known to inhibit microtubule polymerization, also improved cardiac rhythm and Cx43 localization in mdx mice. To phenocopy the effect observed ...
(1987) Phospho-dephospho-control by insulin is mimicked by a phospho-oligosacharide in adipocytes. Nature 330: pp. 77-9Alemany S, Mato JM, Strälfors P (1987) Phospho-dephospho-control by insulin is mimicked by a phospho-oligosaccharide in adipocytes. Nature 330: 77–79...
Su2060 HSP27 Mediated Maintenance of Neural Integrity in Aged Transgenic Mice Expressing Phosphomimic HSP27 来自 Semantic Scholar 喜欢 0 阅读量: 21 作者:S Somara,S Varadarajan,E Zakhem,S Raghavan,RR Gilmont,KN Bitar 摘要: Su2060 HSP27 Mediated Maintenance of Neural Integrity in Aged Transgenic ...
C h ie e n sC hem ia eL let te r sO VI.0 1,No.7,PP.5 3 7 一 5 3 8,199 95 3 7S ynt he s i s of An a l ogs o f P h o s P h o am i noAci ds a nd t hei r B iom i m i eRe a e t i o n so Yn gJ U,Do n ga YnQ IN,uYF e n Z H A O*...
Phospho-mimic HSP20 attenuated the TGF-α-induced JNK signaling in HuH7 cells.Rie, MatsushimaNishiwakiHidenori, ToyodaTomoaki, NagasawaEisuke, YasudaNaokazu, ChibaSeiji, OkudaAtsuyuki, MaedaYuji, KaneokaTakashi, KumadaOsamu, Kozawa
The CD spectra were analyzed with two analysis programs to evaluate the secondary structures of the wild-type and phospho-mimicked dimers and multimers. Result and Discussion The proportion of 尾-strand in the wild-type dimers was very low, particularly in their C-terminal region, including the...
PhosphomimicPhosphomutantMain conclusion The phosphorylation status of MYB75 at T-131 affects protein stability, flavonoid profiles, and patterns of gene expression. Abstract The Arabidopsis transcription factor Myeloblastosis protein 75 (MYB75, AT1G56650) is known to act as a positive transcriptional...
The structural change of multimers slightly depended on the phospho-mimic site. These results suggest that the 尾-strand structure stabilizes the multimerization of XRCC4 and it is regulated by phosphorylation at the C-terminal site in living cells.CONCLUSION\nAn increase in the 尾-strand content...
PhosphomimicPhosphomutantMain conclusion The phosphorylation status of MYB75 at T-131 affects protein stability, flavonoid profiles, and patterns of gene expression. The Arabidopsis transcription factor Myeloblastosis protein 75 (MYB75, AT1G56650) is known to act as a positive transcriptional regulator...
In this study PEPC was cloned from maize and engineered to generate phosphomimic mutant enzyme by conversion of the codon for Serine 15 to aspartate (PEPC S15D ). In vitro study with recombinant wild-type PEPC and phosphomimic PEPC S15D showed that both the enzymes are active catalytically. ...