STAT3 is a 770 amino acid protein with a predicted molecular weight of 88 kDa. It consists of a DNA binding domain, a SH2 domain, a regulatory tyrosine responsible for binding of SH2 domain, and a C-terminal transactivation domain. Distribution Cytosol and nucleus/Ubiquitously expressed Fu...
This antibody detects endogenous protein at a molecular weight of 55 kDa. Purity is >95% by SDS-PAGE. 靶标信息 Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/...
Stat3 (Tyr-705) phosphorylation was inhibited by CYP3A4 silencing, providing a potential mechanism for CYP3A4 involvement in breast cancer cell growth. Silencing Stat3 blocks breast cancer cell growth and abrogates (±)-14,15-EET-induced proliferation, indicating a Stat3 requirement for (±)-14,...
STAT3, one of a family of 7 STAT members, sits at the apex of the signalling cascade and is a potential target for cancer therapy. Small molecular weight inhibitors either prevent STAT3 phosphorylation or target high constitutive levels of phosphorylated pSTAT3 (pSTAT3). Increased constitutive ...
价格:￥电议 更新日期:2024/10/10 15:38:31 生产地:其它 产品型号:BY-3319R 简单介绍:本公司经销Phospho-PDGFRA(Tyr754),磷酸化血小板源性生长因子受体-α抗体,克隆类型为polyclonal,宿主来源是Rabbit,Phospho-PDGFRA(Tyr754)磷酸化血小板源性生长因子受体-α抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询...
et al. Enhancement of hypothalamic STAT3 acetylation by nuclear receptor Nur77 dictates leptin sensitivity. Diabetes 64, 2069–2081 (2015). 16. Zhan, Y. et al. Cytosporone B is an agonist for nuclear orphan receptor Nur77. Nat. Chem. Biol. 4, 548–556 (2008). 17. Zhan, Y. Y. et...
et al. Enhancement of hypothalamic STAT3 acetylation by nuclear receptor Nur77 dictates leptin sensitivity. Diabetes 64, 2069–2081 (2015). 16. Zhan, Y. et al. Cytosporone B is an agonist for nuclear orphan receptor Nur77. Nat. Chem. Biol. 4, 548–556 (2008). 17. Zhan, Y. Y. et...
kl743Bo01 信号传导转录激活因子3(STAT3)多克隆抗体 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3) kl750Ca01 肿瘤坏死因子配体超家族成员13(TNFSF13)多克隆抗体 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13) ...
subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul ...
Antibodies used in Western blot analysis are anti-pERK, anti-pp38, anti-pJNK, anti-pAkt, anti-β-actin, anti-α-Tubulin, anti-PLD1 and anti-pSTAT3 (Cell Signaling Technology, Danvers, MA, USA), anti-caspase-1 and anti-NLRP3 (Adipogen, San Diego, CA, USA), anti-IL-1β (R&D, ...