signaling. All STATs contain an N-terminal oligomerization domain, a DNA-binding domain, and an SH2-association region. STAT1 is phosphorylated at Y701 by receptor-associated Janus kinases (JAKs) leading to STAT1 dimerization and subsequent translocation to the nucleus to activate gene transcription....
For example, to induce phospho-STAT1 (Y701) phosphorylation, macrophages can be activated with IFN纬 or IFN伪, while phospho-ERK1/2 (T202/Y204) is induced in T cells in response to PMA (a phorbol ester, a protein kinase C activator) or CD3 antibodies.Catalog Number...
Phosphorylation of STAT1 on tyrosine 701 by JAK1 and JAK2 is essential for STAT1 dimer formation, nuclear translocation, and DNA binding activity. In response to IFN gamma stimulation, STAT1 homodimerizes or forms heterodimers with STAT3 that can bind to GAS (IFN gamma-...
Phospho-STAT1 (Tyr701) Rabbit Polyclonal Antibody -20ºC保存,Western一抗稀释液-20ºC或4ºC保存,一年有效。Western一抗稀释液优先推荐4ºC保存,长期不使用可以考虑-20ºC保存,但冻融可能会导致出现轻微的浑浊和少量不溶物。 注意事项: 如果本抗体用于Western blot (WB)、免疫荧光(IF)、免疫细胞化学...
中文名称:Anti-phospho-STAT1 (Tyr701) antibody-磷酸化信号转导与转录激活因子1抗体英文名称:phospho-STAT1 (Tyr701) 品牌:沪震生物产地:中国/上海 保存条件:-20°C纯度规格:> 99% 产品类别:抗体 一抗 抗体名:STAT1 (phospho Y701); p-STAT1 (phospho Y701); Phospho-Stat1(pTyr701); STAT1(Phospho-Tyr...
defined in blue, CD4+ T cells are defined in green. BOTTOM: Intracellular staining of unstimulated (orange histogram) or 15-minute IFN gamma-stimulated (purple histogram) normal human peripheral blood cells with Anti-Human phospho-STAT1 (Y701) PE. CD14+ CD4 low monocytes were used for ...
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产品名称:Anti-Stat1 (phospho-Y701) Antibody 产品型号: 产品展商:其它品牌 产品文档:无相关文档 简单介绍 Anti-Stat1 (phospho-Y701)Antibody Anti-Stat1 (phospho-Y701) Antibody的详细介绍 Target Function:Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating...
Phospho-STAT1 (Y701) AlexaFluor405-conjugated Antibody 中文名: 中文别名: CBNumber: CB215324612 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商1 Phospho-STAT1 (Y701) AlexaFluor405-conjugated Antibody化学性质 安全信息 Phospho-STAT1 (Y701) AlexaFluor405-conjugated Antibody性质、用途...