Differential gene enrichment was used to determine immunosuppressed CD8 IL-2 Low and CD8 IFN-纬 Low T cell subsets and differential genes, and candidate molecules closely related to exhausted CD8 T cells were screened based on patient prognosis. Flow cytome...
Single cell sequencing data reveal PHLDA1 as a critical molecule responsible for T cell exhaustion in ovarian cancer 在线阅读 免费下载 引用 收藏 分享 摘要 目的通过绘制高级别浆液性卵巢癌(High-grade serous ovarian cancer,HGSOC)单细胞转录组图谱,筛选并验证与CD8+T细胞耗竭相关的关键基因。方法利用实验...
Anti-T-cell death-associated gene 51 protein Anti-Proline- and histidine-rich protein Anti-Pleckstrin homology-like domain family A member 1 Anti-PQ-rich protein 基本信息 Human Protein Atlas Number【人类蛋白质图谱编号】 HPA019000 Human Protein Atlas characterization data General description【一般描述...
PHLDA1 (HRIP, TDAG51, Pleckstrin Homology-like Domain Family A Member 1, Apoptosis-associated Nuclear Protein, Proline- and Glutamine-rich Protein, Proline- and Histidine-rich Protein, T-cell Death-as 英文名字 PHLDA1 (HRIP, TDAG51, Pleckstrin Homology-like Domain Family A Member 1, Apop...
别名: PQ-rich protein; PQR protein; Proline- and histidine-rich protein; T-cell death-associated gene 51 protein 应用: WB,IHC,ICC 反应种属: Human Specification Aliases PQ-rich protein; PQR protein; P
Pleckstrin homology-like domain family A member 1; PQ rich protein ; PQ-rich protein; PQR protein; Proline- and glutamine-rich protein; Proline- and histidine-rich protein; T cell death associated gene ; T CELL DEATH ASSOCIATED GENE 51; T-cell death-associated gene 51 protein; Tdag; TD...
Background: Granular-cell or clear-cell basal cell carcinomas (BCCs), and clear-cell trichoblastomas have rarely been reported in the literature. PHLDA1 is a follicular stem cell marker, the expression of which has been reported to differentiate trichoepithelioma from BCCs. We wondered whether ...
The FAS antigen is expressed on a broad range of lymphoid cell lines, and is expressed at high levels in T cells subsequent to crosslinking of the T cell receptor (TCR). A previously undescribed protein, TDAG51, restores activation- induced apoptosis in cells that have lost the ability ...
Pleckstrin homology-like domain family member 1 (PHLDA1), also known as T-cell death-associated gene 51 (TDAG51), was first reported to be involved in apoptotic events among adaptive immunity [11], [12]. In recent years, PHLDA1 was shown to participate in tumor progression, including in...
ER-stress, Metabolism, Apoptosis, Cell survival, PHLDA1Pleckstrin homology-like domain, family A, member 1 (PHLDA1) is a multifaceted intracellular protein belonging to the evolutionarily conserved pleckstrin homology-related domain family. Its murine homologue, T-cell death-associated 51 (TDAG51)...