Mice were maintained under specific pathogen-free conditions in a temperature-controlled room (23 ± 1 °C) with a 12/12-hour light/dark cycle and fed ad libitum. Blood samples from human healthy donors were obtained with informed consent from Basque Biobank under the approval of Basque...
As a mucin-specialist, the abundance ofA. muciniphilais closely related to the thickness of the intestinal mucosa. A similar result is found inApoe−/−mice fed western-diet89. Goblet cells, a specialized epithelial cell that secretes mucins, have attracted much attention because of their im...