Phenytoin: Adverse effects in patients with HIV infection: incidence studyAdverse-drug-reactions-incidenceBlood-dyscrasias, drug-inducedHIV-infectionsLiver-disorders, drug-inducedPhenytoin, adverse reactionsSkin-disorders, drug-inducedSkin-eruptions, drug-induced...
Prenatal exposure to phenytoin may increase the risks for congenital malformations and other adverse developmental outcomes [see Use In Specific Populations]. Increased frequencies of major malformations (such as orofacial clefts and cardiac defects), and abnormalities characteristic of fetal hydantoin ...
An increased incidence of major malformations (such as orofacial clefts and cardiac defects) and abnormalities characteristic of fetal hydantoin syndrome (dysmorphic skull and facial features, nail and digithypoplasia, growth abnormalities [including microcephaly], andcognitivedeficits) was reported among chil...
While phenytoin may be an appropriate antiseizure treatment in acute settings, given both acute and chronic adverse effects, drug–drug interactions, and the availability of superior alternatives, phenytoin is not a first-line treatment choice for new-onset epilepsy in the elderly. As with other ...
However, a decrease in pheny- toin serum concentrations has been seen when such a preparation was given with folinic acid to a patient receiving the antiepilep- tic.9 For the effect of phenytoin on busulfan see Effects on the Nervous System under Adverse Effects of Busulfan, p.690. For ...
Four different types of effects were observed in the 52 rats treated with the various polyethylene glycol, surfactant and phenytoin combinations. Polyethylene glycol had a definite necrotic effect on the rectal mucosa of the rat. This adverse effect was more pronounced when phenytoin and polyoxyl 59...
563-5. treatment of adverse effects treatment of poisoning with phenytoin tends to be supportive. repeated doses of activated charcoal may be given orally to adults and children who present within i hour of ingesting more than 20 mg/kg; the aim is not only to prevent absorption but also to...
All patients received prescribed doses; no patient had an injection(s) stopped due to intolerance or side effects. No serious adverse events occurred with intramuscular fosphenytoin. In this study, intramuscular fosphenytoin was demonstrated to be a safe and well tolerated, and in many instances, ...
Although not significant, trends were observed for major side effect in more patients assigned PHT (p = 0.08) and mild side effect in more assigned LEV (p = 0.09). Significance: Both LEV and PHT are well-tolerated perioperatively in parenteral preparation, and in total intravenous-plus-...
Patient and investigator global assessments of overall efficacy (based on a 5-point scale) were two major secondary endpoints. RESULTS: Over the 28-day treatment period, patients treated with fex- ofenadine (n=163) experienced significantly greater improvements in AM, PM and mean TSS than ...