nursing homeagedBackground: Phenytoin (PHT) dosing regimens are often determined based on experience in those aged < 65 years rather than in those aged ≥65 years. Objective: The goal of this study was to determine the impact of sex, age, receipt of concomitant inhibitors or inducers of PHT...
Administration in children. Phenytoin may be given to chil- dren for the control of partial and generalised tonic-clonic sei- zures. It is also used as part of the emergency treatment of status epilepticus and has been used for the prevention and treatment of seizures associated with ...
CARDIOVASCULAR RISK ASSOCIATED WITH RAPID INFUSION The rate of intravenous DILANTIN administration should not exceed 50 mg per minute in adults and 1 to 3 mg/kg/min (or 50 mg per minute, whichever is slower) in pediatric patients because of the risk of severe hypotension and cardiac arrhythmias...
7 If convulsive status epilepticus stopped before administration of the allocated treatment, participants were excluded; however, these participants could be subsequently included if their seizure restarted and required a second-line treatment while in the emergency department. Emergency department team ...
707-9. 13. tse cst, abdullah r. dissolving phenytoin precipitate in central venous access device. ann intern med 1998; 128: 1049. uses and administration phenytoin is a hydantoin antiepileptic used to control partial and generalised tonic-clonic seizures (see epilepsy, p. 539.2). it is also ...
The administration of phenytoin should only be carried out by health professionals who have been appropriately educated and deemed to be competent.MA Healthcare LtdBritish Journal of Neuroscience Nursing
cross-fostered to control mothers at 2 days of age suggesting that the alteration in brain tryptophan metabolism during the development of tryptaminergic neurons in rat offspring, as a result of prenatal phenytoin administration is mediated through changes in lactation or nursing ability of the ...
In patients with renal or hepatic disease, or in those with hypoalbuminemia, the monitoring of unbound phenytoin concentrations may be more relevant [see DOSAGE AND ADMINISTRATION]. With recommended dosage, a period of seven to ten days may be required to achieve steady-state blood levels with ...
Sampling through drug-administration catheter yields falsely elevated phenytoin levels.Reports that two Mercer University pharmacists found sampling serum phenytoin through the same catheter the drug was given in may give misleading high levels, even if the sample is taken hours after the dose and the...