If deuterium is substituted for hydrogen on the 伪 carbon of the side chain then it exhibits profound isotope effects to MAO and its penetration and persistence in the brain is considerably enhanced. In the presence of MAO-B inhibitors treatment with reserpine causes reciprocal changes to PE and...
Phenylethylamine works on the brain similar to amphetamines, and it has comparable side effects. These include nausea, rapid heart rate, jitters, and irritability. Phenylethylamine derived from dietary sources is metabolized quickly by monoamine oxidase B (MAO-B) enzymes. Warning: Do not take phenyl...
We report the toxic effects of 3,4-dimethoxyphenylethylamine (DMPEA), and tetrahydropapaverine (THP) on the rat nigrostriatal system; THP is a tetrahydrois... Isao,Koshimura,and,... - 《Brain Research》 被引量: 12发表: 1997年 Computational study on the conformations of dopamine, its α-...
A. (1974) Identification and distribution of tryptamine in the rat. Can J. Biochem. 52: 447–451. About this Chapter Title Tranylcypromine and an N-Cyanoethyl Analogue: Effects on Brain Levels of the Trace Amines β-Phenylethylamine and Tryptamine Book Title Neuropsychopharmacology of the Trace...
We quantified the effects amphetamine (AMPH), phenylethylamine (PEA), tyramine (TYR), octopamine (OCT) and DA, on initial rates of DA uptake (striatal minces), binding of [3H]mazindol to the neuronal uptake (NU) site (striatal membranes)... EM Parker,LX Cubeddu - 《Journal of Pharmacolog...
The inhibitory effects on monoamine oxidase (MAO) of some dimethylamino-伪-phenylalkylamine derivatives were examined in a rat brain mitochondrial preparat... AL Ask,W Hellstrm,S Norrman,... - 《Neuropharmacology》 被引量: 49发表: 1982年 Synthesis of β-phenylethylamines from styrene derivatives...
Oxidation of β-Phenylethylamine by Both Types of Monoamine Oxidase: Examination of Enzymes in Brain and Liver Mitochondria of Eight Species 1979. Oxidation of β-phenylethylamine by both types of monoamine oxidase: effects of substrate concentration and pH. Life Sci. 25:1231–1236... O Suzuki,Y...
the enantiomerically pure heterofunctionalized P-stereogenicphosphines189or190, respectively (Scheme 48). The latter example of the Diels–Alder reaction exhibited remarkable stereochemical and electronic directing effects, owing to the presence of thenitrogen atomwhich is preferentially located in theexo-po...
1979. Oxidation of β-phenylethylamine by both types of monoamine oxidase: effects of substrate concentration and pH. Life Sci. 25:1231–1236.Suzuki O. , Hattori H. , Oya M. , Katsumata Y. , and Matsumoto T. ( 1979c ) Oxidation of β-phenylethylamine by both types of monoamine oxidase...
- 《General Pharmacology the Vascular System》 被引量: 51发表: 1994年 Alpha 1-adrenergic and 5-HT2-serotonergic effects of some beta-alkoxy-beta-phenylethylamines on isolated rat thoracic aorta Alpha 1-adrenergic and 5-HT2-serotonergic effects of some beta- alkoxy-beta-phenylethylamines on ...