Phenylalanineis anessential amino acid. It is normally degraded via thetyrosinepathway. To enter the tyrosine pathway,phenylalanineis converted into tyrosine by theenzymephenylalanine hydroxylase, which hastetrahydrobiopterinas a cofactor. Deficiency of the enzyme or of its cofactor causes accumulation ofphe...
These results provide evidence for a new biochemical pathway in brain for p-tyramine biosynthesis, with l-phenylalanine (bypassing the formation of l-tyrosine) or 2-phenylethylamine as precursors. The significance and implications of these metabolic routes are discussed, especially considering that p-...
tyrosineEnvironmental stresses such as high light intensity and temperature cause induction of the shikimate pathway, aromatic amino acids (AAA) pathways, and of pathways downstream from AAAs. The induction leads to production of specialized metabolites that protect the cells from oxidative damage. The ...
The mutation responsible for benomyl resistance was determined; it caused a phenylalanine-to-tyrosine change at position 167. Codon usage in the beta-... ORBACH,M. J. - 《Molecular & Cellular Biology》 被引量: 927发表: 1986年 Insulin-induced stimulation of protein phosphorylation in Neurospora ...
Biosynthesis of l-Phenylalanine and l-Tyrosine in the Actinomycete Amycolatopsis methanolica 来自 Semantic Scholar 喜欢 0 阅读量: 52 作者:A.M. Abou-Zeid,GJW Euverink,GI Hessels,RA Jensen,L Dijkhuizen 摘要: Auxotrophic mutants of the actinomycete Amycolatopsis methanolica requiring L-Phe or L-Tyr...
The acute phenylalanine/tyrosine depletion (APTD) method was developed as a safe and rapid way to transiently decreasedopamine(DA) neurotransmission in humans. The method entails the administration of a protein mixture that is selectively deficient in amino acids (AA) that are used to make DA. Si...
Synonyms Acute tyrosine depletion; Acute tyrosine/phenylalanine depletion Definition The acute phenylalanine/tyrosine depletion (APTD) method was developed as a safe and rapid way to transiently decrease dopamine (DA) neurotransmission in humans. The method entails the administration of a protein mixture ...
Phe-free diet and the ratio of specific activity of tyrosine (Tyr) to that of Phe in tissue proteins was also much lower than that for the control diet possibly indicate that the pathway from Phe to Tyr is blocked to a larger extent for adaptation to the Phe-free diet in adult roosters...
Steady state phenylalanine and tyrosine turnover and the rate of conversion of phenylalanine to tyrosine in vivo were determined in 6 healthy postabsorptiv... JTR Clarke,DM Bier - 《Metabolism-clinical & Experimental》 被引量: 334发表: 1982年 Protein blend ingestion following resistance exercise pr...
Phenylalanine and Tyrosine Because mammalianenzymescannot break open thebenzene ringofphenylalanine, the only important pathway for catabolism of thisamino acidis throughhydroxylationtotyrosine. If thephenylalanine hydroxylaseenzymeis lacking, as inphenylketonuria, a high concentration of phenylalanine accumulates...