The synthetic sequence involved carbonation of phenylmagnesium bromide to give (-13C)benzoic acid, reduction with LiAlH4, conversion to the corresponding benzyl chloride followed by preparation of the Grignard reagent and carbonation to produce phenyl (1,2,-13C2)acetic acid. Reaction with 13CH3Li ...
phenylboronic acid Conditions ConditionsYield With lithium In tetrahydrofuran at -10℃; Inert atmosphere; 76% 13283-31-3 borane 98-80-6 phenylboronic acid Conditions ConditionsYield With water; phenylmagnesium bromide In tetrahydrofuran slow addn. of 10 mmol of the Grignard reagent to a...
Pentabromonitrobenzene, pentabromobenzoic acid, pentabromobenzamide, pentabromoacetanilide, barium pentabromobenzenesulphonate, 1,2,4,5 - tetrabromo -3-chloro-6-(trifluoromethyl)benzene, 2,3,5,6-tetrabromo-4-methoxytoluene 2,3,5,6-tetrab... G Deacon,G Farquharson - 《Australian Journal of Chem...
Exposure to air or under heating conditions, easy dehydration, the formation of three molecular polymer. preparation preparation of Phenylboronic acid (laboratory method): phenylgrignard reagent (such as phenylmagnesium bromide) prepared by reaction with a triester of boronic acid, such as trimethyl...
Stage #1: phenylethynylmagnesium bromide; carbon dioxide In tetrahydrofuran at 20℃; under 3000.3 Torr; gas-liquid flow reactor assembly;Stage #2: With polymer-supported sulfonic acid In tetrahydrofuran 75% 2579-22-8 Phenylpropargyl aldehyde A 65-85-0 benzoic acid B 637-44-5 phenylpropyo...
Novel synthesis of polyimide with pendant 1-phenylethyl ester using DBU and its thermal acid-catalyzed deesterification A model reaction of o -( N -phenylcarbamoyl)benzoic acid (amic acid) with threefold amounts of 1-phenylethyl bromide (PEB) and 1,8-diazabicyclo-[5,4,0]-7-u... T Iiz...
To a stirred solution of 3-bromophenylsulfonyl fluoride (D1) (1 g, 4.18 mmol) in dry THF (20 ml) at −78° C., under argon was added phenylmagnesium bromide (1M, 1.4 ml, 4.18 mmol) dropwise. The reaction was left to warm to room temperature overnight and then quenched with ...
Benzyl bromide (0.23 mol) is added dropwise to the mixture. After stirring at room temperature for 5 h, the reaction mixture is poured into 1N HCl (ca. 1000 mL) and extracted twice with EtOAc. The combined extracts are washed with saturated aqueous NaHCO3, brine, dried over MgSO4, and ...
This compound was prepared in a manner analogous to that of Step B of Example 2, with 1.5 grams (0.005 mole) of ethyl N-(4-propoxyphenylmethyl)piperidin-4-ylcarboxylate, 3.4 grams (0.015 mole) of 4-trifluoromethylphenyl bromide, and 0.4 gram (0.015 gram-atom) of magnesium turnings in 15...
4-(Diethyl phosphonomethyl)benzoic acid (66 mmol) was suspended in anhydrous THF (75 mL) under a nitrogen atmosphere. The reaction was cooled in an ice bath while diborane 1M in THF (72.6 mmol ) was added dropwise to the acid. Once the addition was complete the reaction was allowed to ...