In 2012 a medication called Qsymia was approved by the FDA for short and long-term use in helping patients lose weight. Qsymia is a combination of phentermine and Topamax, a migraine preventive drug. In migraine
Phentermine and topiramate、Phentermine/CR topiramate、Phentermine/Topiramate + [5] 靶点 CA2 x CA4 x GABRA1 x TAAR1 作用方式 抑制剂、激动剂 作用机制 CA2抑制剂(碳酸酐酶II抑制剂)、CA4抑制剂(碳酸酐酶IV抑制剂)、GABRA1激动剂(gamma-aminobutyric acid type A receptor subunit alpha1 agonists) ...
Phentermine/topiramateER is an oral combination of immediate-release phentermine hydrochloride and ERtopiramate(25). Phentermine is asympathomimeticamineanorectic agentapproved in 1959 for the short-term treatment of obesity at a dose of 30 mg (free base) by mouth once a day. Topiramate is a sulfa...
MarkFeldmanMD, inSleisenger and Fordtran's Gastrointestinal and Liver Disease, 2021 Phentermine/Topiramate Low-dose, controlled-releasephentermineplus topiramate (as 1 capsule) was approved by the FDA in 2012 as a long-term treatment for obesity. Phentermine is an adrenergic agonist that promotes weig...
Vivus’ proprietary oral capsule containing phentermine and extended-release (ER) topiramate has been approved in the US for the treatment of obesity. Phentermine is an appetite suppressant, while topiramate is an antiepileptic medication. The once-daily formulation, known as Qsymia™, is designed ...
Elderly are at high risk for myocardial infarction, hypertension, angina, or becoming dependent on phentermine with prolonged use Discontinue if weight loss has not occurred with 4 weeks of therapy Not approved for long-term use Discontinue if tolerance develops, and do not exceed recommended dosage...
Qsymia is indicated in combination with a reduced-calorie diet and increased physical activity to reduce excess body weight and maintain weight reduction long term in: Adults and pediatric patients aged 12 years and older with obesity Adults with overweight in the presence of at least one weight-...
Since obesity is considered a chronic metabolic disease [2], this agent is approved for long-term use. Here we present a case of a patient with obesity and SRED treated with phentermine–topiramate extended release (PHEN-TPM ER), resulting in the dual benefit of weight loss and resolution ...
I know the drug isn't a long-term solution for better health. But it's a great jump-start and it's helping me break out of the cycle-- gain weight > feel crappy > lose motivation > gain more weight > repeat. I'm working to develop healthy habits for sustained health and continued...
It is indicated only for short-term treatment. Tolerance develops. Common adverse effects include dry mouth, insomnia, increased blood pressure, and constipation. Phentermine/Topiramate Combination of phentermine and the anticonvulsant topiramate (Qsymia). This drug induces more weight loss than ...