Respiratory phenotypes are distinctly affected in mice with common Rett syndrome mutations MeCP2 \\{T158A\\} and \\{R168X\\} (2014). Respiratory phenotypes are distinctly affected in mice with common Rett syndrome mutations MeCP2 T158A and R168X. Neuroscience 267, 166-176... M J.,Bisso...
It is not only genes that are the cause of numerous disorders our children are facing but, also the surrounding (both living and nonliving) that lays an impact, thus changing the "gene expression," thus changing a whole lot of traits. Conclusions: Genes are affected by several factors and ...
Phenotypic alterations become visible at distinct developmental stages, both in affected human fetuses and in zebrafish, whereas early stages of development are apparently normal. The zebrafish phenotypes caused by nup88 deficiency are only ... E Bonnin,P Cabochette,A Filosa,... - 《Biorxiv》 被...
In social insects, identical genotypes can show extreme lifespan variation providing a unique perspective on age-associated microbial succession. In honey bees, short- and long-lived host phenotypes are polarized by a suite of age-associated factors including hormones, nutrition, immune senescence, and...
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Whole exome sequencing identifies variable expressivity of CLN6 variants in Progressive myoclonic epilepsy affected families Progressive myoclonic epilepsies (PMEs) are a group of neurodegenerative disorders, predominantly affecting adolescents and, characterized by generalized w... M Ilyas,F Tariq,R Ishaq...
For genes with multiple ASE measurements, the SNP with the lowest p-value was taken to represent the gene for that individual, since several of the potential underlying mechanisms of ASE, such as splicing and transcript truncation (followed by NMD), are position-specific and cannot be accurately...
By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection. See our privacy policy for more information on the use of your perso...
(2013) observed that the models show the same prediction capacity when the traits are affected by many small-effect loci. The highest mean square error observed for Y* may be due to this parameter follows the magnitude of the pseudo-phenotype. Fernandes Júnior et al. (2016) evaluated ...
The utilization of a PCA approach seems to have been particularly efficient in detecting individuals that are different for a global multitrait phenotype rather than for a particular trait, as supported by the high overall significance achieved in the differential expression experiment. In the next ...