EnvironmentGene-environment interactionsIsoniazidN-acetyltransferase 2 (NAT2) metabolize several drugs including isoniazid. We investigated the effect of genotype, geographical difference, and smoking habit on NAT2 phenotype in Ethiopians.Aklillu, EleniAntonio Carrillo, JuanMakonnen, EyasuBertilsson, Leif...
M. Pervasive modulation of obesity risk by the environment and genomic background. Genes 9, E411 (2018). Article PubMed CAS Google Scholar Machiela, M. J. & Chanock, S. J. LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles ...
Ethnicity and Environment May Affect the Phenotype of Immune Thrombocytopenic Purpura in Children THOMAS KU¨ HNE, WILLI BERCHTOLD, TRAN VAN BE, TRAN VAN BINH, AND PAUL IMBACH Division of Oncology/Hematology [T.K., P.I.], University Children's Hospital Basel, Basel, Switzerland; University of...
Parenting is considered a phenotype that can be influenced by nature and nurture. Genetic contributions to parenting are conceptualized as evidence of genotype–environment correlation (rGE). Early BG studies focused on demonstrating that some parenting dimensions were heritable due to passive and ...
An inherited condition, FH is distinguished by high levels of cholesterol, to be precise, the LDLs (low-density lipoproteins). It is seen to affect 1 in 500 individuals and is a common disorder. Sickle cell This characteristic can take place in a heterozygous environment. Here, the allele ...
The outer appearance of an organism or the visible physical characteristics are known as phenotypes. When genes express themselves externally, that is the phenotype of that organism. It is like the “final product” that is shaped by our genes and the environment we live in. It includes physica...
variations introduced by different growth seasons and environment did not negatively affect HairNet so long as some data representing the condition to test was also present in the training set. Overall, we demonstrated that this simple imaging set-up combined with HairNet is able to reproduce the...
the Classification of Periodontal and Peri-Implant Diseases and Conditions recommended the uniform use of “periodontal phenotype”, which not only describes both soft and bone tissue conditions, but also emphasizes its variability influenced by genotype, clinical treatment, and environment factors (5)....
Dispersal increased or decreased lifetime reproductive success depending upon an individual's natal environment and phenotype. Many of the phenotypic traits and environmental conditions that influenced lifetime reproductive success also influenced dispersal, such as clutch size and competition, and this ...
In addition to myriad genetic contributions, understanding the biological basis of complex traits is further challenged by the variation in multi-dimensional system-wide endophenotypes that can be dynamic and influenced by the environment, a concept that emerged initially in neurobiological genomics34. Lik...