The phenothiazine group of drugs is among the most widely prescribed psychotropic drugs in the world [17]. The phenothiazines are classified as typical antipsychotics because of their high potency to blockade the D2 receptor. These drugs can be effective in treating the positive symptoms but not ...
A large family of drugs derived from phenothiazine, a compound that in itself is too poisonous for human consumption. Phenothiazine derivatives include tranquilizers, medications that prevent vomiting, antihistamines, and drugs used to enhance the effectiveness of anesthesia. ...
The paper presents three personal cases about the use and complications of drugs of the phenothiazine group with particular reference to prochlorperazine (Compazine). In the three cases, the drug prochlorperazine was being used in the...
The term antipsychotic refers to a group of drugs effective in the treatment of psychosis including schizophrenic, paranoid, schizoaffective, bipolar disorder, and other psychotic disorders. Traditional antipsychotic agents have phenothiazine structure chemically. Phenothiazinene drugs are adrenergic blocking ...
The widespread use of standard leucotomy terminated in the early 1950's with the advent of the phenothiazine group of drugs. But since then, psychosurgical... PK Bridges,JR Bartlett - 《Postgraduate Medical Journal》 被引量: 13发表: 1973年 Comparison of thioridazine and chlorpromazine in doctor...
Excited-state Properties and In Vitro Phototoxicity Studies of Three Phenothiazine Derivatives This work concerns a combined photophysical, photochemical and photobiological study of three drugs (psychotherapeutic agents) of the phenothiazine series:... F Elisei,L Latterini,GG Aloisi,... - 《Photochemistr...
A simple, rapid and sensitive method for the determination of six phenothiazine drugs, either in pure form or in pharmaceutical formulations, is described. The method is based on the formation of stable phenothiazine free radical by the use of potassium periodate as the chromogenic reagent in ...
Phenothiazines (PTZs) have been used for the antipsychotic drugs for centuries. However, some of these PTZs have been reported to exhibit antitumor effects by targeting various signaling pathways in vitro and in vivo. Thus, this study was aimed at exploi
Although an insufficient number of patients received both drugs to make a direct comparison, it is the writers' impression that chlorpromazine in equivalent doses is somewhat more effective in reducing anxiety and tension than NP207. 3. NP207 and BOL 148 combined did not show a superior action...
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