1. 适应症与用法(Indications and Dosage) 苯巴比妥主要用于控制癫痫发作和治疗失眠。对于癫痫患者,建议的初始剂量通常为每天一次30-60毫克,根据个体反应逐渐调整剂量。而治疗失眠时,建议剂量通常为每天服用100-200毫克,可以在睡前服用。 2. 用药注意事项(Precautions) 在使用苯巴比妥之前,应该告知医生是否对苯巴比妥...
In order to find the optimal dosage schedule of phenobarbitone for neonatal convulsions, four groups of patients were studied. Twelve infants (group 1) received a mean phenobarbitone dose of 9.5 mg/kg a day given intramuscularly for 3 days followed by 5.8 mg/kg a day given intramuscularly ...
Nahat MC, Masuoka T, Edwards RC (1988) Developmental aspects of phenobarbital dosage requirements in newborn infants with seizures. J Perinatol 8:318–320Nahata MC,Masuoka T,Edwards RC.Developmental aspects of phenobarbital dosage requirements in newborn infants with seizures.Journal of Perinatology. ...
doses of phenobarbital. As tolerance to phenobarbital develops, the amount needed to maintain the same level of intoxication increases; tolerance to a fatal dosage, however, does not increase more than two-fold. As this occurs, the margin between an intoxicating dosage and fatal dosage becomes ...
Phenobarbital is available in the following dosage forms that are taken by mouth. 20 mg/5 mL oral elixir 15 mg, 16.2 mg, 30 mg, 32.4 mg, 60 mg, 64.8 mg, 97.2 mg, 100 mg oral tablets Phenobarbital is also available in injectable forms. ...
Dosage du Phenobarbital, de la phenytoine et de la Primidone Dans le Serum Par Chromatography en Phase GazeusePhenobarbitalphenytoinprimidonegas-liquid chromatographytherapeutic drug monitoringA gas-liquid chromatographic method for the simultaneous determination of phenobarbital, phenytoin and primidone in ...
under phenobarbital sodium. it meets also the requirements for ter each use. sterility tests·71Ò, uniformity of dosage units·905Ò, and labeling under injections·1Ò. usp reference standards·11Ò— usp camphor rs usp phenol rs identification—the retention times of the camphor and phe...
to 7.6 mg/L in a woman taking 150 mg daily. Phenobarbital concentrations in milk were less than those in simultaneous maternal serum samples in all cases.[5] Using the values in this paper, the average weight-adjusted infant dosage was 72.5% (range 39 to 135%) of the maternal dosage. ...
barbital plasma concentrations had fallen from 16 to 8 micrograms/ml and an increase in the phenobarbital dosage to 150 mg daily was required to restore concentra tions. the tipranavir/ritonavir component of haart ther apy was considered to be responsible. for the possible effect of ...
injection. On the third day of therapy, trough concentration was determined; elimination rate constants were calculated using the two concentrations and the total dosage administered. Maintenance doses were adjusted to achieve desired serum concentrations, and predicted concentrations were compared with ...