Kennedy RK, Veena V, Naik PR. Phenazine-1-carboxamide (PCN) from Pseudomonas sp. strain PUP6 selectively induced apoptosis in lung (A549) and breast (MDA MB-231) cancer cells by inhibition of antiapoptotic Bcl-2 family proteins [J]. Apoptosis, 2015, 20: 858-868...
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Mesoporous silica nanoparticles (MSNPs) were synthesized via base-catalyzed sol-gel process at room temperature, functionalized with phenazine-1-carboxamide (PCN) and characterized by UV-visible, FT-IR, DLS, XRD spectroscopic techniques, SEM, TEM, TGA and BET analysis. Native MSNPs, PCN and PCN...
This study provides important basis for further engineering P . chlororaphis for high PCN production and efficient glycerol conversion. 展开 关键词: Pseudomonas chlororaphis, Phenazine-1-carboxamide, Glycerol, Metabolomics, 13C, Channeling DOI: 10.1186/...
1-hydroxyphenazine and PCN.26In addition, PCN has important physiological roles, including Fe acquisition, due to its redox-activity like other phenazines such as pyocyanin, PCA and 1-hydroxyphenazineinter alia.22PCA, along with its hydroxylated analog, 2-hydroxy-PCA, contributes to pathogen inhib...
Phenazine‑1‑carboxamide (PCN)Extracellular electron transfer (EET) is believed to be a bottleneck in microbiologically influenced corrosion (MIC), also known as biocorrosion, by electro-active microbes. However, there is a lack of any direct evidence at the genetic level to confirm this so ...
chlororaphis strains with high-yield PCN production. To achieve this, the lon gene was knocked out in wild-type P. chlororaphis HT66 and the breeding mutant P3 strain with a non-scar deletion strategy. The resulting HT66螖lon and P3螖lon mutants produced a significantly higher PCN production...
Additionally, indoor toxicity and the in vitro control effect of PCN were further studied to determine its potential mechanisms of action on B. cinerea. PCN was inhibitory against B. cinerea with a 50% effective concentration (EC50) of 108.12 渭g/mL; the toxicity of PCN was equivalent to ...
Freundlich adsorption coefficient Kf of PCN ranged from 5.75 to 12.8 [(mg/kg)/(mg/L)1/n] in soils. The retention factor Rf values ranged from 0.0833 to 0.354, which means that the mobility of PCN in the three types of soil is between immobile to moderately mobile. Our results ...
fungi, also reduced PCN levels. Different nitrogen sources greatly influenced PCN levels. Analysis of autoinducer levels at conditions of high and low PCN production demonstrated that, under all tested conditions, PCN levels correlate with autoinducer levels, indicating that the regulati...