phe-tRNA 释义 [医]苯丙氨酰tRNA
Aminoacyl‐tRNA synthetases (ARSs) canonical function is to conjugate specific amino acids to cognate tRNA that are required for the first step of protein synthesis. Genetic mutations that cause dysfunction or absence of ARSs result in various neurodevelopmental disorders. The human phenylalanine‐tRNA...
Based on the model, residues Lys262 and Arg305 are closer to tRNAPhe (<10 Å), while the other four residues (Cys76, Phe252, Arg401, and Thr461) have a longer distance (>15 Å) from tRNAPhe. None of these residues are directly involved in the interaction with tRNA. Download: ...
修饰核苷对酵母tRNA phe反密码区域的贡献 维普资讯 http://www.cqvip.com
tRNAImino groupsRNA resonance assignmentPost-transcriptional modificationsTransfer RNAs (tRNAs) are heavily decorated with post-transcriptional modifications during their biosynthesis. To fulfil their functions within cells, tRNAs undergo a tightly controlled biogenesis process leading to the formation of mature...
Katunin V, Soboleva N, Mahkno V, Sedelnikova E, Zhenodarova S, Kirillov S. Effect of the nucleotide-37 on the interaction of tRNA(Phe) with the P site of Escherichia coli ribosomes. Biochimie. 1994; 76 (1):51–57.Katunin, V., Soboleva, N., Mahkno, V., Sedelnikova, E., ...
【答案】:其中的(a)Phe和(b)His可能只存在一种tRNA。因为tRNAPhe的反密码子是GAA,因此它可按照摆动规则与Phe的密码子UUU和UUC配对。tRNAHis的反密码子是GUG,它可与His的密码子CAC和CAU配对。但由于Leu有六种简并密码子(UUA、UUG、CUU、CUC、CUA和CUG),根据摆动规则,至少需要三种反密码子(UAA...
Naturally occurring nucleoside modifications are an intrinsic feature of transfer RNA (tRNA), and have been implicated in the efficiency, as well as accuracy-of codon recognition. The structural and functional contributions of the modified nucleosides in the yeast tRNA(Phe) anticodon domain were examin...
采用1HNMR方法研究了镧离子对酵母tRNAPhe分子结构和构象变化的影响 .结果表明位于扩大二氢尿嘧啶螺旋 (D-螺旋 )的端梢三级碱基对 (G-15) (C-4 8)明显受加入La3+ 的影响 ,向低场位移 0.33;与三级相互作用相关 ,连接D-茎和接受茎起固定L结构转折的 (U-8) (A-14)碱基对向高场位移 0.20 ;另一可能受...
4.铕离子对tRNA^(Phe)结构影响的NMR研究 涂华民 ,杨燕生 ,龚孟濂 - 波谱学杂志 - 1998第2期 5.功能性电刺激对急性脑梗死大鼠运动功能及室管膜下区的溴氧尿嘧啶核苷+/神经胶质纤维酸性蛋白+细胞表达的影响 刘慧华 ,燕铁斌 ,李胜活 - 中华物理医学与康复杂志 - 2012第003期 查看全部 收藏 ...