17、Zhang G, mTOR regulates phase separation of PGL granules to modulate their autophagic degradation...
Electrostatic phase separation: AMhatre, S., Vivacqua, V., Ghadiri, M., Abdullah, A.M., Al-Marri, M.J., Hasanpour, A., Hewakandamby, B., Azzopardi, B., and Kermani, B. (2015) `Electrostatic Phase Separation: A Review. Chemical Engineering Research and Design. Institution of ...
Phase separation has been documented at key cell division structures, namely, the spindle pole (centrosomal and acentrosomal), spindle body, kinetochore, inner centromere, chromosomes, and elsewhere (Figure 1; Table 1). In this review, we focus on the function, properties, and key components of...
Phase separation of the RPA complex is stimulated by ssDNA Collectively, these findings raised the possibility that RPA forms condensates owing to protein properties linked to phase separation. To further explore this possibility, we expressed and purified the untagged human tRPA complex over three sequ...
大量的研究表明这凝集体通常富集了含有多个介导分子内部或分子间相互作用元素的多价分子,它们会自发聚集,形成寡聚物或聚合物,而由于熵驱动效应,这种自发聚集将降低分子的溶解度,从而促进相分离发生,富集特定分子1,2。多价分子主要包括含有模块化结...
Phase separation is vital for multiple physiological processes. By leveraging missense variants that alter phase separation propensity, we develop a machine learning approach named PSMutPred to predict the impact of missense mutations on phase separation. PSMutPred demonstrates robust performance in ...
Diffusiophoresis promotes phase separation and transport of biomolecular condensates. bioRxiv https://doi.org/10.1101/2023.07.03.547532 (2023). Izri, Z., van der Linden, M. N., Michelin, S. & Dauchot, O. Self-propulsion of pure water droplets by spontaneous marangoni-stress-driven motion. ...
(5–30 nm). Multi-length scale domains, lateral and vertical phase separation, and interconnected network-like charge transport pathways are some of the key morphological features that lead to enhanced open-circuit voltage, short circuit current, fill factor, and in turn, greater power conversion ...
Review article Asymmetric wettability fibrous membranes: Preparation and biologic applications Composites Part B: Engineering Journal 2024,Composites Part B: Engineering MingyuZhang, ...Deng-GuangYu 3.4Phase separation Phase separation, as a top-down preparation method, is a routine method for preparing ...
As mentioned earlier, emerging evidence indicates the involvement of LLPS in various cellular processes. Methods to study liquid separation are being developed (to observe LLPS); we review them below. Several tools have been developed to predict the ability of targeted proteins to undergo phase sep...