Diblock polymers are a widely used material for structures1. The microstructure of a diblock polymer changes depending on the synthetic conditions. The process of the change in microstructure is spinodal decomposition, and various phase-separated structures, such as lamellar, cubic, hexagonal, and gyro...
Phase-separated EB1 provided a compartment for enriching tubulin dimers and other plus-end tracking proteins. Real-time imaging of chromosome segregation in HeLa cells expressing LLPS-deficient EB1 mutants revealed the importance of EB1 LLPS dynamics in mitotic chromosome movements. These findings ...
In the aforementioned cases of crack propagation, the material model implementation is restricted to a single phase, as common phase-field crack models only consist of two phase formulations: a crack and a solid phase. Therefore these implementations do not have to deal with phase-field-specific ...
Large clients should be separated with respect to database infrastructure to minimize the impact on maintenance and availability. Build the Logical Design The logical design is the second step in creating the solution design. After identifying the business and user needs in the conceptual design, the...
varies smoothly with temperature. The solid–liquid transition is indicated by a sharper horizontal (along the compositionx-axis) jump, which we expect would become discontinuous in the large system size limit. The width of the approximate discontinuity indicates the width of the phase-separated ...
A recent study reported that SpmX also has the capability to be phase separated32. Our results confirmed the generation of liquid droplets using 5 µM SpmX(∆TM)-mCherry under the same assay conditions as PodJ (Supplementary Fig.10a). To dissect the molecular mechanism of SpmX regulation...
hindering the formation of conventional secondary structures. Over 80% of proline residues are located in the coil regions of secondary structures (Supplementary Fig.5d). In our previous study9, the experimental results suggest that two segments of GP-enriched key residues predicted by PSPHunter in...
As a control, HA-mNG-VP35 expressed alone phase separated in the cytoplasm (Fig.1c). Most cells have large quantities of small (sub-µm) VP35-containing dense phases (condensates) with high apparent mobility relative to the dilute phase, but a small number of condensates had a larger ...
摘要: Our group has for many years synthesized polymers with different architectures in order to be able to control and predict structures and properties.We have studied different tools to create these advanced structures;most recently using new advanced initiators....
Thus, it should be noted that varying the percentages (or weight ratio) of the different conjugates in the composite hydrogel can produce different phase-separated structures. This may be at least in part due to the fact that the ratio of the conjugate precursors in the reaction can affect th...