In this review, we discuss the ways in which recent studies of low-complexity (LC) domains have challenged our understanding of the mechanisms underlying cellular organization. LC sequences, long believed to function in the absence of a molecular structu
Susanne Parke & Katrin Roth Pharmacovigilance, Bayer AG, Berlin, Germany Kerstin Gude Data Science UK, Bayer PLC, UK Fabrizio Messina Contributions FM, KG, KR, and SP designed the study. All authors interpreted the data, wrote the manuscript, and approved the final version for publication. Corr...
2023 Efficacy and Safety of Proposed Biosimilar Natalizumab (PB006) in Patients With Relapsing-Remitting Multiple SclerosisThe Antelope Phase 3 Randomized Clinical Trial Bernhard Hemmer, MD1; Heinz Wiendl, MD2; Karsten Roth, PhD3; et al Hendrik Wessels, PhD3; Josef Höfler, PhD4; Cyrill Hornus...
SXM Festival 2023 lineup include Black Coffe, Loco Dice, Camelphat, Marco Carola and more Beginning with Grammy Award-winning South African musicianBlack Coffeeand co-founder of the Desolat record labelLoco Dice, the Phase 2 roster for SXM Festival also includes Puerto Rican native Natalia Roth, ...
which was dropped on a TEM grid. Accelerating voltage of 300 kV was used for the measurement. In order to perform in situ TEM measurements, a cross-sectional TEM sample was lift out from the perovskite film and welded on a Cu lift-out grid using focused ion beam (FIB, Tescan GAIA3)...
Roth-Albin I, Mai SHC, Ahmed Z, Cheng J, Choong K, Mayer PV. Outcomes following advanced wound care for diabetic foot ulcers: a Canadian study. Can J Diabetes. 2017;41(1):26-32. doi:10.1016/j.jcjd.2016.06.007 PubMedGoogle ScholarCrossref 23. Logesh...
and the immune system attacks HBV-infected hepatocytes, resulting in decreased HBV DNA levels and elevated ALT levels. However, some CHB patients with similar characteristics fall outside the above ranges, and are considered indeterminate. For instance, indeterminate CHB patients are usually characterized...
Andrea.Rubbert-RothDivision of Rheumatology, Cantonal Hospital St Gallen, St Gallen, Switzerland.Bochao.JiaEli Lilly and Company, Indianapolis, USA.Luna.SunEli Lilly and Company, Indianapolis, USA.Yushi.LiuEli Lilly and Company, Indianapolis, USA.Thorsten.Holzkmper...
Patients with Coronavirus disease 2019 exhibit low expression of interferon-stimulated genes, contributing to a limited antiviral response. Uncovering the underlying mechanism of innate immune suppression and rescuing the innate antiviral response remain
N6-methyladenosine (m6A) is the most abundant internal mRNA nucleotide modification in mammals, regulating critical aspects of cell physiology and differentiation. The YTHDF proteins are the primary readers of m6A modifications and exert physiological fu