meiosisx-inactivationIn some cells pairing of homologous chromosomes happens at particular moments during the cell life cycle. A Statistical Mechanics model based on some experimental data is presented and discussed here for this phenomenon. Under this model, chromosomes pair at special regions whose ...
Meiosis is the process where 4 genetically unique haploid daughter cells are produced. These are produced in the sexual organs, creating sperm in men and oocytes in females. During meiosis I, homologous chromosomes are split apart, while in meiosis II...
Chromosomal Influence on Meiotic Spindle Assembly: Abnormal Meiosis I in Female Mlh1 Mutant Mice In mouse oocytes, the first meiotic spindle is formed through the action of multiple microtubule organizing centers rather than a pair of centrosomes. Alth... Woods,M L. - 《Journal of Cell Biology...
To determine whether ATR has a role in the end-ligation phase of CSR, we analyzed CSR junctions using high-throughput genome-wide translocation sequencing (HTGTS)32. While junctions recovered from non-homologous end-joining (NHEJ)-deficient B cells (e.g., DNA-PKcs-/-, Xrcc4-/-) displayed...
(Ding et al.2019). A recent compelling study in yeast demonstrated that several meiosis-specific lncRNAs and their binding proteins form condensates via LLPS on several specific loci. These condensates assist with chromosome pairing by their fusion, creating a link between homologous chromosomes at ...
meiosisx-inactivationIn some cells pairing of homologous chromosomes happens at particular moments during the cell life cycle. A Statistical Mechanics model based on some experimental data is presented and discussed here for this phenomenon. Under this model, chromosomes pair at special regions...