Swales NJ, Caldwell J (1997) Phase 1 and 2 metabolism in freshly isolated hepatocytes and subcellular fractions from rat, mouse, chicken and ox livers. Pestic Sci 49:291-299Nicola J S. Caldwell J. Phase 1 and 2 Metabolism in Freshly Isolated Hepatocytes and Subcellular Fractions from Rat,...
“Phase I and Phase II” Drug Metabolism: Terminology that we Should Phase Out?: Drug Metabolism Reviews: Vol 37, No 4 Click to increase image sizeClick to decrease image size PD Josephy,FP Guengerich - 《Drug Metabolism Reviews》 被引量: 64发表: 2005年 Terminology and the Construction ...
网络二期反应 网络释义 1. 二期反应 药物-1 第二期反应(Phase II metabolism) 不能发生第一類反应的药物,或经过第一類反应后的代谢产物极性仍不 够高的,可在 … ja.scribd.com|基于 1 个网页
Fromm. Phase I and II metabolism and MRP2-mediated export of bosentan in a MDCKII-OATP1B1-CYP3A4-UGT1A1-MRP2 quadruple- transfected cell line. Br J Pharmacol. 2013; 169 (1): p. 21-33.Fahrmayr C, Konig J, Auge D, Mieth M, Munch K, Segrestaa J, et al. Phase I and II ...
the lack of MCPs is not the result of a phototrophic metabolism, but may be connected to the unidirectional flagellar motor of Rhodobacter sphaeroides.doi... RE Sockett,JP Armitage,MC Evans - 《Journal of Bacteriology》 被引量: 165发表: 1987年 Periplasmic nitrate-reducing system of the phototr...
Human phase I metabolism of the novel synthetic cannabinoid 5F-CUMYL-PEGACLONE Additionally, 31 samples containing the recently surfaced synthetic cannabinoid Cumyl-PeGaClone (5-pentyl-2-(2-phenylpropan-2-yl)-2,5-dihydro-1H-pyrido[... L Mogler,S Halter,M Wilde,... 被引量: 0发表: 2018年...
(b) A treatment suspected to have apharmacokineticorpharmacodynamicinteraction with other treatments used for neuro-oncology patients, such as a drug whose metabolism is altered by enzyme-inducingantiepileptic drugs(Prados et al., 2004). (c) A treatment whose toxicity might be additive with the ...
Phase 1 metabolism of toxicants and metabolic interactions. In: Stuart RC, Hodgson E (eds) Molecular and biochemical toxicology, 4th edn. John Wiley and Sons, Hoboken, pp 173–203E. Hodgson, "Phase 1 metabolism of toxicants and metabolic interactions," in Molecular and Biochemical Toxicology,...
Fluorometric screening for metabolism-based drug–drug interactions - ScienceDirect Inhibition of cytochromes P-450 (CYP) is a principal mechanism for metabolism-based drug interactions. In vitro methods for quantitatively measuring the ex... CL Crespi,DM Stresser - 《J Pharmacol Toxicol Methods》 ...
In addition, using the serum threshold level of ⩽45 μg/ml as identified in the phase 2 study in prostate cancer, was also associated with longer survival, suggesting that this effect is not isolated to one tumor type.17 Larger randomized phase III studies in NSCLC will be required to ...