showed that patients with advanced prostate cancer can be treated safely with the cellular immunotherapy with promising therapeutic activity, according to the study published in Nature Medicine.
This study is an open-label, single-center, phase 1/1b first-in-human dose escalation and expansion clinical trial using concurrent IT and IV nivolumab. The study consisted of two parts: a phase 1 dose escalation portion and a phase 1b dose expansion cohort at the recommended dose. Each ...
Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects of AOC 1020 Administered Intravenously to Adult Patient... The aim of this 2-part first-in-human study was to assess the safety, tolerability, pharmacokinetics, and pharmacodynamic effects on proximal...
Real-world effectiveness and safety of simnotrelvir/ritonavir for COVID-19: A nationwide, multicenter, prospective, observational cohort study in China 2024, Journal of Infection Show abstract Clinical development of antivirals against SARS-CoV-2 and its variants 2024, Current Research in Microbial ...
The 20-valent pneumococcal conjugate vaccine (PCV20): expected added value 工程文摘(无原文件) 2024-12-17 11:48 0 0 20%肺炎球菌结合疫苗(PCV20):预期附加值 The 20-valent pneumococcal conjugate vaccine (PCV20): expected added value 工程文摘(无原文件) 2024-12-17 11:51 0 0 20%肺炎球...
Fig. 1: Study design. a, The Cell-based Medicinal Product used for transplantation originated from non-immortalizedhfNPCs (BI-0194-008 cell line) obtained from the telencephalon and diencephalon of a single 10–12 weeks post-conception (WPC) human fetus, after elective pregnancy termination.hf...
Research grant / Funding (institution): AstraZeneca, Bristol-Myers Squibb, Boehringer Ingelheim, Janssen Cilag, Merck, Novartis, Pfizer, Roche, Sanofi ; Travel / Accommodation / Expenses: AstraZeneca, Bristol-Myers Squibb, Merck (MSD), Roche; Speaker Bureau / Expert testimony: Roche/Genentech, Br...
Given the critical role of HNF-1α in regulating PCSK9 and ANGPTL3 transcription, our study reveals that targeting HNF-1α may serve as a potential therapeutic strategy for hypercholesterolemia treatment. HNF-1α is a transcription factor highly expressed in the liver and regulates the ...
Focusing on international sci-tech frontiers and serving the country's major development demands, the CSNS has supported research in the fields of energy, physics, materials and engineering, such as studies on aerospace components, lithium-ion batteries, solar cell, rare earth magnetism, high-tempera...
AMPLIFY-201 is a multicenter, open-label, dose-ranging Phase 1 study designed to evaluate the safety and tolerability of the ELI-002 two-peptide formulation (ELI-002 2P). The trial enrolled a total of 25 individuals—including 20 with pancreatic d...