Such hubris had to end in tears, of course, and phase I studies on azolastone, which commenced in 1983, revealed that the new molecular miracle provoked profound and irreversible thrombocytopenia in patients [13], particularly so on a repeat-dose schedule [14]. A companion poster from the ...
Hydrometrocolpos In subject area: Pharmacology, Toxicology and Pharmaceutical Science The term hydrometrocolpos describes distention of the vagina and uterus. From: Obstetric Imaging: Fetal Diagnosis and Care (Second Edition), 2018 About this pageSet alert On this page On this page...
This systematic review and meta-analysis describes the various adverse events associated with PD-1 and PD-L1 inhibitor drugs reported in clinical trials
Tordera RM, Pei Q, Sharp T (2005) Evidence for increased expression of the vesicular glutamate transporter, VGLUT1, by a course of antidepressant treatment. J Neurochem 94:875-883. ArticlePubMedCASGoogle Scholar Torres GE, Gainetdinov RR, Caron MG (2003) Plasma membrane monoamine transporters...
(Sec); the exception is the selenoprotein P that has near 10 s residues (for a brief description of selenoproteins function, see the legend of Fig.1). The incorporation of selenium into the seryl-carbon skeleton is complex and occurs at the level of the transfer RNA (t-RNA[Ser]Sec) (...
Lombard S, Helmy ME, Pieroni G. Lipolytic activity of ricin from Ricinus sanguineus and Ricinus communis on neutral lipids. Biochem J. 2001;358:773-78111535138Google ScholarCrossref 43. Pappenheimer AM Jr, Olsnes S, Harper AA. Lectins from Abrus precatorius and...
In the management of patients with multiple sclerosis (MS), providers are all faced with the highly formidable challenge of ascertaining whether, and to
Histocompatibility antigens are cell surface glycoproteins that play critical roles in interactions among immune system cells. From: Elsevier's Integrated Review Immunology and Microbiology (Second Edition), 2012 Featured on this page Chapters and Articles You might find these chapters and articl...
In these individuals, COVID-19 progresses to severity at later phases of the infection time-course. In this situation, the viral load may persist at very high levels with a subsequent massive host-cell lysis that could trigger the cytokine storm. In severe and critical patients, viral dynamics...
2020). The most characteristic clinical course of severe COVID-19 patients is the development of ARDS. This life-threatening lung condition prevents sufficient oxygen from crossing the alveoli into the blood. Therefore, to increase oxygen to the lungs, patients are put on mechanical ventilators. ...