insulin.210In this way, these tumors promote cell proliferation in an autocrine manner.30,211IGF-2 also binds to the IGF-1R, whereas IGF-1 binds to its own IGF-1R and to hybrid receptors of IGF-1R and IR-A as w
The Allium genus, encompassing garlic, onion, chives, and related species, has been an integral part of traditional medicine for centuries due to its remarkable pharmacological properties. This review consolidates current insights into the therapeutic potential of Allium species, focusing on their divers...
Regular Articles select article Effect of statin use on cardiovascular events and all-cause mortality in immune-mediated inflammatory diseases: A systematic review and meta-analysis involving 148,722 participants Research articleAbstract only Effect of statin use on cardiovascular events and all-cause mort...
In fact, we observed a dose-dependent reduction in the consumption of caffeine with increasing severity of st-eatosis in the general population. This effect has been observed in animal models of fatty liver, in which caffeine intake improves insulin resistance and reduces inflammatory cytokine ...
[81]. This break allows for restoring regular monoamine oxidase activity [81]. The case of a 57 year-old man presents the risk of combining bupropion with drugs that are mild reversible monoamine oxidase inhibitors with weak potency. As a result of a bypass graft infection, linezolid was ...
The glutathione (GSH) system is considered to be one of the most powerful endogenous antioxidant systems in the cardiovascular system due to its key contribution to detoxifying xenobiotics and scavenging overreactive oxygen species (ROS). Numerous invest
In the present pharmacological space, distinctive interactions are more probable than non-distinctive interactions. Non-distinctive interactions are regular as they conform to the similarity principle. Distinguishing among the distinctive interactions requires precision. The range ofdis much higher than that ...
which is involved in the process by which SOD converts oxygen into H2O2and subsequently catalysis the breakdown of H2O2into H2O. GSH-Px (glutathione peroxidase) can precisely catalyze the reaction between GSH and H2O2, minimizing the production of peroxides and preserving regular physiological processes...
of these drugs. The consensus is that the occurrence of ocular adverse reactions can be minimised by close attention to the dose (which should be set on a body weight basis) with regular (e.g. quarterly) retinal examination. Although HCQ and CQ can pass through the placenta, the use of ...
The glutathione (GSH) system is considered to be one of the most powerful endogenous antioxidant systems in the cardiovascular system due to its key contribution to detoxifying xenobiotics and scavenging overreactive oxygen species (ROS). Numerous invest