Pharmacokinetics of diclofenac sodium (Voltaren) and metabolites in patients with impaired renal function. Scan J Rheumatol 1978; Suppl. 22: 30–5Stierlin H, Faigle JW, Colombi A (1978) Pharmacokinetics of diclofenac sodium (Voltaren) and metabolites in patients with impaired renal function. Scand ...
This work relates to the development and the in vitro evaluation of sustained-release minitablets (MT), prepared by melt granulation and subsequent compres... J Goole,F Vanderbist,K Amighi - 《Int J Pharm》 被引量: 169发表: 2007年 Release characteristics of diclofenac sodium from encapsulated...
Methods: Female Wistar rats were submitted to complete section of the spinal cord at the T8 level. SCI and sham-injured rats received 3.2 mg kgÀ1 of diclofenac sodium either intravenously or orally, diclofenac concentration was measured in whole blood samples and pharmacokinetic parameters were ...
内容提示: · 918·中圆医药工业杂志Chi nese J ournal of Pharm aceuti cal s2008,39( 12)双氯芬酸钠缓释胶囊的人体药动学及生物等效性张伟t,秦玉花1,赵红卫1,宋建伟2,赵钰敏1( 1.河南省人民医院药剂科,河南郑州450003:2.郑州大学医学检验中心,河南郑州450052)摘要:18名男性健康志愿者单剂量和多剂量交叉...
8.Pharmacokinetics of the preparation of diclofenac sodium chitosan eye drops in aqueous humor of rabbits双氯芬酸钠壳聚糖滴眼液兔眼药动学 9.The Effect of Danshen on Steady State Warfarin Pharmacodynamics and Pharmacokinetics in Rats;丹参注射液对大鼠体内稳态华法林药动学和药效学参数的影响 10.Clinical...
Biovavailability Study of Commercial Sustained-Release Preparations of Diclofenac Sodium in Gastrointestinal Physiology Regulated-Dogs The gastrointestinal (GI) physiology of beagle dogs was regulated with a combined-treatment of intramuscular pentagastrin (10 渭g/kg脳2) and intravenous at... 相良,一禎...
- Xenobiotica; the fate of foreign compounds in biological systems 被引量: 11发表: 2011年 Clinical Pharmacokinetics of Diclofenac Diclofenac is a nonsteroidal anti-inflammatory drug ( NSAID ) of the phenylacetic acid class. When given orally the absorption of diclofenac is rapid and ... DNM ...
Recent studies corroborate the clinical relevance of rectal drug therapy, and the value of the rectal route as an alternative to parenteral administration has been assessed for several drugs, e.g. diazepam, midazolam, morphine and diclofenac.TRUNCATED AT 400 WORDS) 展开 关键词: Humans Administration...
We obtained data to evaluate the two formulations by the pharmacokinetics and safety with bioequivalence of ibuprofen and demonstrated the bioequivalence of the T formulation. In the fasting and fed study, we found that diclofenac sodium sustained-release tablets were taken with fo...
干预 Group A:Muti-dose Thalidomide;GroupB:Muti-dose Thalidomide and Diclofenac sodium enteric-coated tablets 招募状态 Completed 开始时间 2010-05-10 性别 不限 最小年龄 18 最大年龄 45 年龄组 Adult 国家列表 China 结果指标 Plasma concentration 试验详情 暂无权限 试验历程 全球临床试验历...