Pharmacokinetics refers to how the body impacts the drug's effectiveness. It comes from two Greek terms: pharmakon meaning 'drug' and kinetikos meaning 'moving or putting in motion'. It has four components: Absorption - Happens when the drug enters the blood circulation. It can either be ente...
"Luftmensch," literally meaning "air person," is the Yiddish way of describing someone who is a bit of a dreamer. Did You Know? The word "infant" comes from the Latin word "infans" which literally means "unable to speak; speechless." ...
Cova D, Lorusso V, Silvestris N. The pharmacokinetics and pharmacodynamics of drugs in elderly cachectic (cancer) patients. In: Mantovani G. Cachexia and Wasting: A Modern Approach. Springer Milan, 2006: 377-382.Cova D, Lorusso V, Silvestris N. The pharmacokinetics and pharmacodynamics of ...
Pharmacokinetics and pharmacodynamics of Da-Cheng-Qi decoction in the liver of rats with severe acute pancreatitis
This review aimed to integrate the current knowledge on posaconazole pharmacokinetics, pharmacodynamics, major toxicity, existing resistance, clinical experience in special populations, and new therapeutic strategies in order to get a clear understanding of the clinical use of this drug....
Both exposure and maximum plasma concentration show linear dose proportional pharmacokinetics (PK) over a 0.15-8mg/kg dose range. In healthy adults, the clearance (CL) is 10.4mL/h/kg and volume of distribution is 0.2L/kg; both are independent of the dose. Micafungin is metabolized by ...
This randomized clinical trial compares the pharmacokinetics and pharmacodynamics of orally administered Δ9-tetrahydrocannabinol (THC)-dominant and
Pharmacokineticsand pharmacodynamics of tacrolimus inliver transplant recipients: inside the white blood cells[J]. Clin Biochem, 2015, 48(6): 406-11.Lemaitre F, Blanchet B, Latournerie M, et al. Phar鄄 macokinetics and pharmacodynamics of tacrolimus in liver transplant recipients: inside the ...
5Pharmacokinetics (PK) 5.1Absorption Propofol is only suitable for intravenous use. It is not suitable for enteral or other routes of administration due to its bitter taste and low oral bioavailability caused by a high first-pass effect and the high hepatic extraction rate (> 90%) [24]. ...
Isepamicin is an aminoglycoside antibacterial with properties similar to those of amikacin, but with better activity against strains producing type I 6R