Spray-freeze-drying in the manufacture of pharmaceuticals - European Pharmaceutical ReviewDrug ManufacturingUniversity of Oxford
It is widely used in freeze-drying of fruits, vegetables, meat, Chinese herbal medicines, health care products, etc.Industrial and mining enterprises, colleges and universities, biological products, food processing, agricultural science, chemical pharmacy, medical units and powder drying and baking unde...
Spray Drying vs. Freeze Drying For Pharmaceutical Formulationsis the preferred choice for preserving a wide range of pharmaceutical formulations when stability in the liquid state is inadequate, storage requirements are too stringent, or a solid form of the product is desired. However, recent research...
Many drying technologies are available but the sensitive nature of active pharmaceutical ingredients requires gentle drying of active pharmaceutical ingredients APIs.
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In SEM analysis of nanoparticles after freeze-drying and shadowing, shrinking of the particles may be anticipated. The determined particle sizes should thus be considered as the absolute lower size limit; size statistics should not be calculated from such values (Bootz et al., 2004). An ...
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Pharscin Pharma has applied advanced modernpharmaceutical technologies such as CO2 supercritical extraction, ultrasonicoscillation extraction and new processes of macroporous resin adsorption purification,ultra-low temperature pulverization, vacuum belt drying and vacuum freezedrying to manufacture premium products....
In some embodiments, at least part of the solvent is removed by conventional drying methods such as freeze drying or spray drying to obtain a concentrated nanosuspension.In some embodiments, fluidized bed granulation is used to remove solvent from the nanosuspension to obtain a concentrated ...