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Here we report the use of a fluorescein-tagged peroxisomal targeting sequence peptide (F-PTS1, acetyl-C{K(FITC)}GGAKL) for investigating pH regulation of glycosomes in live procyclic form Trypanosoma brucei. When added to cells, this fluorescent peptide is internalized within vesicular structures...
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It can be seen from Table 3, compared with the Res group, the absorption param- eter (Ka) and effective permeability (Peff) of Res in each intestinal segment in rats of the αCT/Res-JNP group were increased (Ka increased 1.13–1.60-fold, Peff increased 1.14–1.66-...
ph = pka it is worth mentioning that this equation is occasionally written for the ka value instead of the pka value, so you should be familiar with the relationship: pka = -logka the henderson-hasselbalch equation’s assumptions because it excludes water chemistry from the equation, the ...
Full size image Human metastatic breast cancer cells (MDA-MB-231 cells) seeded on type I collagen migrate in the direction of higher pHevalues in a gradient of 0.2–0.3 pH units/mm [166]. The slope of this gradient would correspond to a gradient of 0.02 units per single cell length and...
When IGD-Targeted was injected in tumor-bearing mice, since the pH value around tumor tissues was acidic, i-motif structure could form, IGD-Targeted could further recognize GD2, and Dox could be released into tumor cells. Normal tissues could be protected due to neutral pH v...
Myrsini Sakarika, ... Korneel Rabaey The re-emergence of methylotrophic microbial protein The first microbial isolate able to consume a C1 compound – methane – was reported in 1906 [19], paving the way for the discovery of the methylotrophic metabolism. A few decades later, the global fo...
Full size image Mechanism discussion of oxidative self-polymerization Gallic acid nanoparticles (GA-NPs) were identified by LC-MS in negative ion mode, the mass-to-charge radio changed from m/z 170 to m/z 322 at 2 h of reaction, the synthesis mechanism was inferred that polymer produced ...
Full size table Equilibrium swelling behavior Figure 3 shows the effect of time on the degree of swelling of Cs-g-PAAm hydrogel, Cs-g-PAAm/AuNPs, Cs-g-PAAm/AgNPs and Cs-g-PAAm/Au–Ag-NPs nanocomposites at three different pH values (1.5, 5.4, and 7.4). The degree of swelling increment...