PGRP-SC2 DERIVED FROM OPLEGNATHUS FASCIATUS AND USES THEREOFThe present invention relates to: peptidoglycan recognition protein-SC2 (OfPGRP-SC2) derived from Oplegnathus fasciatus, consisting of an amino acid sequence of SEQ ID NO: 2; and uses thereof. The OfPGRP-SC2 protein of the ...
melanogaster SC2 cells. PGRP-SA was then purified, crystallized and its crystal structure was determined by molecular replacement using PGRP-LB18 as a starting model (see Materials and Methods, and Table 1). The final refined model consists of residues 11–177 of the cloned sequence corresponding...
Downregulation of the Drosophila immune response by peptidoglycan-recognition proteins SC1 and SC2 PLoS Pathogens, 2 (2006), pp. 139-147 Google Scholar Bosco-Drayon et al., 2013 V Bosco-Drayon, M Poidevin, I G Boneca, K Narbonne-Reveau, J Royet, B Charroux Peptidoglycan sensing by the...
亲疏水性,信号肽,二级结构,细胞定位,三级结构等的分析.结果 获得一段长920 bp的编码美洲螯龙虾PGRP的cDNA序列,包含一个长834 bp的开放阅读框,编码277个氨基酸;编码蛋白是含有信号肽的分泌蛋白,含有1个C端PGRP结构域,表明是一种PGRP;分析结果显示该蛋白与黑腹果 蝇(Drosophila melanogaster)短型PGRP-SC2和PGRP-SD...
亲疏水性,信号肽,二级结构,细胞定位,三级结构等的分析.结果获得一段长920 bp的编码美洲螯龙虾PGRP的cDNA序列,包含一个长834 bp的开放阅读框,编码277个氨基酸;编码蛋白是含有信号肽的分泌蛋白,含有1个C端PGRP结构域,表明是一种PGRP;分析结果显示该蛋白与黑腹果蝇(Drosophila melanogaster)短型PGRP-SC2和PGRP-SD...
The predicted amino acid sequence of AiPGRP shared high identity with PGRP in other organisms, such as PGRP precursor in Trichoplusia ni and PGRP SC2 in Drosophila melanogaster. A quantitative reverse transcriptase Real-Time PCR (qRT-PCR) assay was developed to assess the mRNA expression of Ai...
The expression and localization of pgrp-sc2/PGRP-SC2 in A.sinica during embryonic development and bacterial challenge were determined by qPCR, WB and ISH. During different A. sinica embryonic development stages, the expression level of pgrp-sc2/PGRP-SC2 was most highly expressed at 0 and ...
PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan. Cell. 2014; 156 :109–122.Guo L, Karpac J, Tran SL, Jasper H. PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan. Cell. 2014; 156 (1-2):109–22....
PGRP-SC2PRRImmune responsePGRPs (Peptidoglycan recognition proteins) could recognize peptidoglycan and play vital roles in innate immunity among different animals. Till present, the functions of PGRP have b... 查看全部>>doi:10.1016/j.dci.2018.07.008Hui Yang a...
The coding regions of zfPGRP6 (zf: zebrafish), zfPGRP2-A, zfPGRP2-B and zfPGRP-L contain five exons and four introns; however, the other PGRP-like genes including zfPGRPSC1a, zfPGRPSC2, tnPGRP-L1-, tnPGRP-L2 and frPGRP-L (fr: Takifugu rubripes) contain four exons and three ...