The microarray technology has recently entered CGH allowing for the analysis of the full set of 23 pairs of chromosomes in a few hours without the need for embryo cryopreservation. Because this is a new form of screening and has only been used in a small number of cases, it is not yet ...
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Array CGH (aCGH) result turnaround is 24 hrs. We aimed to determine the error rate using aCGH on single cells compared to FISH and what percentage of abnormal embryos would be detected by FISH compared to aCGH. DESIGN: Embryos donated for research (avg. maternal age 32.7) had one cell ...
Aim: Preimplantation Genetic Diagnosis (PGD) has been widely applied to reciprocal translocation carriers, using FISH with specific probes for chromosomes involved in the translocation. However, the aim of this study was to perform a more comprehensive PGD using the Short-CGH procedure, which allows...
PGDPGSArray CGHCGHAneuploidyEmbryosPreimplantation genetic diagnosis for aneuploidy has become a fairly routine part of assisted reproductive technology worldwide. While the theory of aneuploidy screening makes scientific sense, no...doi:10.1007/978-1-4419-1780-5_53Gary Harton...
OBJECTIVE: Comparative genome hybridization (CGH) is successfully applied to trophectoderm biopsy, but it is not compatible with a fresh embryo transfer. Array CGH (aCGH) result turnaround is 24 hrs. We aimed to determine the error rate using aCGH on single cells compared to FISH and what perc...