Volumetric muscle loss (VML) injury is characterized by a non-recoverable loss of muscle fibers due to ablative surgery or severe orthopaedic trauma, that results in chronic functional impairments of the soft tissue. Currently, the effects of VML on the
1e). In addition, we evaluated the cell cycle distribution of miR-23b-3p-knockdown MNNG-HOS and MG63 cells, and found that the G1-phase population was increased, whereas the S-phase population was decreased compared with their negative control (NC) cells using flow cytometry (Fig. 1f). ...
22.Viatte L, Nicolas G, Lou DQ, Bennoun M, Lesbordes-Brion JC, Canonne-Hergaux F, Schönig K, Bujard H, Kahn A, Andrews NC, Vaulont S. Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice. Blood. 2006; 107:...
(a) Schematics representing control and VML injured TA muscle, showing the region of interest evaluated during imaging and representative 2D images from the respective regions from transgenic mice that ubiquitously expressed mitochondrial Dendra2 GFP. (b) Representative 3D reconstruction of mitochondrial ...
(BET) inhibitor treatment. A super-enhancer region highly occupied by the BET family member BRD4 was identified for thePGC-1αgene. BET inhibitor treatment prevented this interaction, leading to a dramatic reduction of PGC-1α expression. Accordingly, BET inhibition diminished respiration and ...
Fig. 2: Effects of PTSD diagnosis on cerebellar subregion volumes. Atlas-based effect size (Cohen’sd) maps and MNI-based coronal slices (top:y = −72; bottom:y = −54) of the significant between-group differences for cerebellar subregion volumes in PTSD vs. Controls. Negative...
Foundation of China (32172902), the National Key R&D Program of China (2022YFD1801102), Key Research and Development Program of Gansu Province (20YF8NA028), Special project for transformation of scientific and technological achievements in Inner Mongolia Autonomous Region of China (2021CG0024-02)....