The Influence of Sport Specific Social Organizations on the Development of Identity: A Case Study of a Professional Golf Management Program In 1951, the Professional Golfer's Association (PGA) code of ethics included a passage describing the necessity for a professional golfer to uphold the spo.....
The secretion and quality control of glycosylphosphatidylinositol-anchored proteins (GPI-APs) necessitates post-attachment remodeling initiated by the evolutionarily conserved PGAP1, which deacylates the inositol in nascent GPI-APs. Impairment of PGAP1 activity leads to developmental diseases in humans and...
Previous genetic studies, consisting of FMR1 gene, AIP gene, array CGH and metabolic studies (including transferrin glycosylation assay) showed normal results. This study was approved by the Ethics Committee of the Radboud University Medical Center (Commissie Mensgebonden Onderzoek, regio Arnhem-...
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The orphan nuclear receptor Nurr1 is critical for the development, maintenance and protection of midbrain dopaminergic (mDA) neurons. Here we show that prostaglandin E1 (PGE1) and its dehydrated metabolite, PGA1, directly interact with the ligand-binding domain (LBD) of Nurr1 and stimulate its...
The secretion and quality control of glycosylphosphatidylinositol-anchored proteins (GPI-APs) necessitates post-attachment remodeling initiated by the evolutionarily conserved PGAP1, which deacylates the inositol in nascent GPI-APs. Impairment of PGAP1 activity leads to developmental diseases in humans and...