(PFK.2/FBPase.2)是糖代谢的一种重要的信号酶,通过影响2,6.双磷酸果 糖水平实现对糖酵解通路的调节。在哺乳动物中有四种不同的PFK-2/FBPase一2 同工酶,分布于不同的组织,如肝、肌、心、睾丸及脑等,分子量及生物学 活性均存在差别,与正常组织相比在肿瘤细胞中PFK.2/FBPase.2有较高水平的 ...
PFK-2FBP酶Fructose-6-phosphate 2-kinase and fructose 2,6-bisphosphatase have been partially purified from maize leaves by PEG fractionadon and by chromatography on TSK-DEAE ion exchanger and Blue-Sepharose 4B. Fructose-6-phosphate 2-kinase was activated by phosphate and inhibited by 3-pnospho...
摘要: 6-磷酸果糖激酶-2/果糖双磷酸酶-2(PFK-2/FBPase-2)是糖代谢的一种重要的信号酶.此酶是一种双功能酶,在酶蛋白中具有两个独立的催化中心.PFK-2/FBPase-2通过影响2,6-双磷酸果糖水平实现对糖酵解通路的调节.该文主要介绍PFK-2/FBPase-2的基因结构特点、同工酶,以及在肿瘤中的表达、调控等.关键词:...
PFK-2/FBPase-2 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) catalyses the synthesis and degradation of Fru-2,6-P2 (fructose 2,6-bisphosphate), a ... L Novellasdemunt,L Bultot,A Manzano,... - 《Biochemical Journal》 被引量: 69发表: 2013年 Increased activity of the tandem ...
为研究糖酵解关键酶果糖-6-磷酸-2激酶/果糖-2,6-二磷酸酯酶(6-phosphofructo-2-kinase/fructose-2,6- bisphosphatase,PFK-2/FBPase-2)基因转录水平与宰后肉品质间的关系,根据猪PFK-2/FBPase-2 mRNA序列 (GenBank登录号:NM_001143721.1)设计一对特异性引物并选择β-ac
大致过程是：insulin/glucagon 影响 PFK2/FBPase2 影响 F26BP 影响 PFK1/FBPase1 影响 glycolysis趋势...
6 P2ASE brain/placenta type isozyme; 6PF 2-K/Fru 2,6 P2ase 3; fructose 6 phosphate,2 kinase/fructose 2, 6 bisphosphatase; Inducible 6 phosphofructo 2 kinase/fructose 2,6 bisphosphatase; iPFK 2; IPFK2; PFK/FBPase 3; PFK-2; PFK2; Renal carcinoma antigen NY REN 56; uPFK 2; PFKFB...
Upregulation of heart PFK-2/FBPase-2 isozyme in skeletal muscle after persistent contraction[J] . Jordi Rovira,Jose Maria Irimia,Mario Guerrero,Joan Aureli Cadefau,Roser Cussó.Pflügers Archiv - European Journal of Physiology . 2012 (4)
6Phosphofructo-1-kinase catalyses the first irreversible step of glycolysis, and is activated by fructose-2,6-bisphosphate, a product of the kinase activity of four bifunctional isoenzymes, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase (PFK-2/FBPase-2:PFKFB1-4). These are potential anti...
Massa L, Baltrusch S, Okar DA, Lange AJ, Lenzen S, Tiedge M: Interaction of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) with glucokinase activates glucose phosphorylation and glucose metabolism in insulin-producing cells. Diabetes 53:1020-1029, 2004...