Fig. 1 | BNT162b2 vaccine induces robust germinal center B cell and TFHcell response in mice. a, Experimental timeline and tests. FACS, fluorescence-activated cell sorting; ICS, intracellular cytokine staining. b, Serum ...
The emergence of the SARS-CoV-2 variant of concern Omicron (Pango lineage B.1.1.529), first identified in Botswana and South Africa, may compromise vaccine effectiveness and lead to re-infections1. Here we investigated Omicron escape from neutralization by antibodies from South Africanindividuals ...
来自专栏 · VACCINE 37 人赞同了该文章 辉瑞(Pfizer)公司和BioNTech宣布,在全球启动其新冠mRNA疫苗的2/3期临床研究,预计将招募3万名志愿者,主要用于评估其基于mRNA的新冠候选疫苗BNT162b2预防COVID-19的安全性和有效性。 这项2/3期临床试验为随机、设盲研究,预计招募3万名18-85岁的参与者,接种剂量为30 µ...
2021年，Bali Pulendran在Nature发表文章Systems vaccinology of the BNT162b2 mRNA vaccine in humans，...
Pfizer-BioNTech COVID-19 Vaccine(also known as BNT162b2) This product information is intended only for residents of the United States. Emergency uses of COVID-19 vaccines from BioNTech and Pfizer, including Pfizer-BioNTech COVID-19 Vaccine (2024-2025 Formula), have not been approved or license...
Despite the success of the BNT162b2 mRNA vaccine, the immunological mechanisms that underlie its efficacy are poorly understood. Here we analyzed the innate and adaptive responses to BNT162b2 in mice, and show that immunization stimulated potent antibody
Global Information About Pfizer‑BioNTech COVID‑19 Vaccine (also known as BNT162b2 or as COMIRNATY) The approval status of the Pfizer‑BioNTech COVID‑19 Vaccine varies worldwide. For countries where the relevant regulatory authority has not authorised the vaccine or has not authorised it...
pfizer-biontech covid-19 vaccine (also known as bnt162b2) pfizerpen® (penicillin g potassium) piperacillin and tazobactam (piperacillin and tazobactam) plegisol® (potassium chloride, sodium chloride, calcium chloride, and magnesium chloride) potassium acetate (potassium acetate) potassium chloride ...
Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) today announced the initiation of a rolling submission to the European Medicines Agency (EMA) for BNT162b2, the lead candidate from the companies' vaccine development program against COVID-19...
With this, we now know the exact mRNA contents of the BNT162b2 vaccine, and for most parts we understand why they are there: The CAP to make sure the RNA looks like regular mRNA A known successful and optimized 5’ untranslated region (UTR) ...