中文名称:化合物 PfDHODH-IN-2英文名称:PfDHODH-IN-2 CAS:425629-94-3品牌:TargetMol 产地:美国保存条件:Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. 纯度规格:98.90%产品类别:抑制剂 货号:T8767 ...
PfDHODH-IN-2 | MedChemExpress(MCE) 英文名称: 总访问: 82 国产/进口: 进口 半年访问: 1 产地/品牌: MedChemExpress(MCE) 产品类别: 生化试剂 规格: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg 最后更新: 2024-11-4 货号: HY-W078844 CAS 号: 425629-94-3 参考报价: 电询 立即询价 电话咨询 ...
中文名称:化合物 PfDHODH-IN-1英文名称:PfDHODH-IN-1 CAS:183945-55-3品牌:TargetMol 产地:美国保存条件:Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. 纯度规格:99.74%产品类别:抑制剂 货号:T12438 ...
PfDHODH-IN-1价格:￥电议型号:T12438原产地:中国大陆 更新时间:2025/2/13 11:32:11 产品摘要:PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis. PfDHODH-IN-1 has antimalarial activity....
英文名 PfDHODH-IN-2 中文别名 英文别名 KUN29943; KUN 29943; KUN-29943; 分子式 C13H12ClNO3S 分子量 297.76 用途 生物活性 PfDHODH-IN-2, a dihydrothiophenone derivative (Compound 11), is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor with an IC50 of 1.11 µM...
PfDHODH-IN-2详情 评价(0) 货号:ajcx31284 CAS:425629-94-3 别名:2-[((4-氯苯基)氨基]-4-氧代-4,5-二氢噻吩-3-羧酸乙酯 分子式:C13H12ClNO3S 分子量:297.76 纯度:>98% 溶解度:DMSO: 12.5 mg/mL (41.98 mM); Water: < 0.1 mg/mL (insoluble) ...
183945-55-3 化学名称 化合物PFDHODH-IN-1 CAS No.183945-55-3 分子式C14H11F3N2O2 分子量296.24 LogP2.88 (Predicted) 别名PfDHODH-IN-1; 查看所有 183945-55-3 性质 密度1.5±0.1 g/cm3 (Predicted) 沸点445.8±45.0 °C at 760 mmHg (Predicted) 闪点223.4±28.7 °C (Predicted) 熔点212 -...
(2012) Lead Hopping for Pf DHODH Inhibitors as Antimalarials Based on Pharmacophore Mapping, Molecular Docking and Comparative Binding Energy Analysis (COMBINE): A Three-Layered Virtual Screening Approach. Molecular Informatics 31 :10.1002/minf.v31.10, 711-718 /...
PharmacophorePfDHODHQSARVirtual screeningMalaria is a major worldwide public health threat securing the fifth position among the top ten causes of worldwide death with worrying social and economic burdens due to the rapid emergence of resistance to the currently available antimalarial drugs like ...
PfDHODHMalariaDSM-265Malaria remains a significant threat to human health worldwide with increasingly serious challenges being faced due to emerging drug resistance. DSM-265 is a potent and selective triazolopyrimidine-based inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) and kills...