SE Asia has long been fertile ground for the development of antimalarial resistance. This region earlier saw the former first-line therapies CQ and sulfadoxine + pyrimethamine succumb to resistance, which then migrated into Africa14,15. The failure of CQ had devastating consequences in Africa,...
total RNA could not exclude the involvement of other classes of noncoding or non-canonical transcripts such as microRNAs, long noncoding RNAs and circular RNAs. Recent work has shown that the output of protein-coding genes shifts to circular RNAs by a process of back-splicing under conditions w...