泰康生命医学中心的宋威团队与武汉大学中南医院老年医学科的叶旭军团队在 Nature 上发文： A novel antidiuretic hormone governs tumour-induced renal dysfunction ，在肠道肿瘤细胞分泌物中鉴定到果蝇中第一例明确的抗利尿素—— F 亚型离子转运肽（ITPF），它会破坏果蝇的肾功能，导致严重的腹胀。
1. Dysfunction or low regulation of immunesystem such as immunodeficiency disease, chronic infection and adjuvantchemotherapy for cancer. 2. Low endocrine regulation or disorders suchas diabetes, fatty liver, cirrhosis, nephritis, renal failure adjuvant therapy. 3. Regeneration of nerve system such as...
泰康生命医学中心的宋威团队与武汉大学中南医院老年医学科的叶旭军团队在 Nature 上发文: A novel antidiuretic hormone governs tumour-induced renal dysfunction ,在肠道肿瘤细胞分泌物中鉴定到果蝇中第一例明确的抗利尿素—— F 亚型离子转运肽(ITPF),它会破坏果蝇的肾功能,导致严重的腹胀。
体内活性Oral administration of PF-1355 reduces plasma MPO activity, vascular edema, neutrophil recruitment, and elevates circulating cytokines. In a model of anti-glomerular basement membrane disease, albuminuria and chronic renal dysfunction are completely suppressed by PF-1355 treatment [1]. ...
Oral administration of PF-1355 reduces plasma MPO activity, vascular edema, neutrophil recruitment, and elevates circulating cytokines. In a model of anti-glomerular basement membrane disease, formerly known as Goodpasture disease, albuminuria and chronic renal dysfunction are completely suppressed by PF...
three-dimensional reconstruction of the coronary microvascular network (Vesselucida360), as well as vasodilator coronary arteriole dysfunction are associated with the development of LV diastolic dysfunction, which were improved by the treatment with the selective PDE9A inhibitor, PF04447943 (3 mg/kg/da...
[1]. Lansdell MI, et al. Discovery of a selective small-molecule melanocortin-4 receptor agonist with efficacy in a pilot study of sexual dysfunction in humans. J Med Chem. 2010 Apr 22;53(8):3183-97. [2]. Modi ME, et al. Melanocortin Receptor Agonists Facilitate Oxytocin-Dependent Part...
Microglia play a pivotal role in neurodegenerative disease pathogenesis, but the mechanisms underlying microglia dysfunction and toxicity remain to be elucidated. To investigate the effect of neurodegenerative disease-linked genes on the intrinsic proper
腹腔镜直肠膨出修补术:镜下打开直肠阴道间隙至会阴体,将会阴体缝合至直肠阴道隔、闭合直肠阴道筋膜缺损 网片修补术:以网片作为替代材料,加强后壁支持 桥式修补术:保留部分阴道后壁粘膜,加强后壁支持 盆底功能障碍 (Pelvic Floor Dysfunction) 盆腔脏器脱垂( Pelvic Organ Prolapse, POP ) 压力性尿失禁(Stress Urinary...
LOX-1, the receptor for oxidized low-density lipoprotein identified from endothelial cells: implications in endothelial dysfunction and atherosclerosis. nuclear factor-κBNK natural killernatural killerLectin-like oxidized low-density lipoprotein (LDL) receptor-1 (LOX-1) was initially identified as the ...