Parkinson disease (PD) is a common neurodegenerative pathology, whose accurate diagnosis is still a challenge. PET imaging obtained with [18F]-fluorodeoxyglucose provides a metabolic pattern, highlighting the brain substructures related to PD, thus constituting a valuable diagnosis tool. Besides, it has...
doi:10.1016/J.NICL.2018.11.004Franziska AlbrechtTommaso BallariniJane NeumannMatthias L. SchroeterElsevierNeuroImage: Clinical
Dopamine depletion and microstructural degradation underlie the neurodegenerative processes in Parkinson's disease (PD). To explore early alterations and underlying associations of dopamine and microstructure in PD patients utilizing the hybrid positron emission tomography (PET)-magnetic resonance imaging (MRI...
Parkinson's disease (PD) is a neurodegenerative synucleinopathy characterized by the degeneration of neuromelanin (NM)-containing dopaminergic neurons and deposition of iron in the substantia nigra (SN). How regional NM loss and iron accumulation within specific areas of SN relate to nigro-striatal ...
doi:10.1016/j.jns.2017.08.098PicciniP.Journal of the Neurological Sciences
Purpose To construct multivariate radiomics models using hybrid F-FDG PET/MRI for distinguishing between Parkinson's disease (PD) and multiple system atrophy (MSA). Methods Ninety patients (60 with PD and 30 with MSA) were randomised to training and validation sets in a 7:3 ratio. All ...
241051 Introduction: Parkinson's disease (PD) is a neurodegenerative disease that affects more than 10 million individuals worldwide. Patients with PD experience cognitive impairment and debilitating symptoms, such as rigidity, tremors, and freezing of gait. Physicians rely on imaging via magnetic ...
Diagnostic value of brain MRI and 18F-FDG PET in the differentiation of Parkinsonian-type multiple system atrophy from Parkinson's disease. Eur J Neurol. 2008;15:1043-1049.Kwon KY,Choi CG,Kim JS,et al.Diagnostic value of brain MRI and 18F-FDG PET in the differentiation of Parkinsonian-type...
Comparison of brain MRI and 18 F-FDG PET in the differential diagnosis of multiple system atrophy from Parkinson’s disease. Mov Disord. 2007;22(16):2352–8.Kwon KY, Choi CG, Kim JS, Lee MC, Chung SJ. Comparison of brain MRI and 18F-FDG PET in the differential diagnosis of mul- ...
In a normal brain the spatial distribution of resting cerebral blood flow and cerebral metabolic rate of glucose are closely related. A relatively new MR technique, Arterial Spin Labeling (ASL), is used to measure brain perfusion. It produces perfusion weighted images in aLK Teune...