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Natural microbial communities are complex biological systems. They are typically composed of a large number of different species and a high extent of strain-level diversity [1]. Moreover, they can be highly dynamic, influenced by microbial dispersion/migration, variation in physicochemical properties ...
Unlike viral delivery systems, lipid nanoparticles (LNPs) meet all of these criteria. They have been extensively validated both pre-clinically and clinically for the delivery of small interfering RNA (siRNA) (Thi et al., 2014; ClinicalTrials.gov identifier: NCT01960348) and mRNA (Richner et al...
With the development of the field of communication systems and networking, the number of network devices has sharply increased. Popular on-line platforms such as Facebook have further increased the network traffic data [8,9]. It is becoming more challenging to achieve accurate NTP [10]. There ...