They also note that constipation is the most common and persistent side effect of opioids which can relieve moderate to severe pain if in higher potency.TomasMariaJavierNoelEBSCO_AspMedicine & Health Rhode Island
If side effects occur (significant constipation, fatigue, gastrointestinal symptoms, hypotension, edema), we recommend decreasing the dose and adding a second-line agent such as melatonin, topiramate, or gabapentin. Although two open-label studies with divalproic acid for chronic cluster h...
This patient, of Italian origin, was first hospitalized at the age of 6 weeks with 3 weeks' history of vomiting, constipation, and failure to thrive. On admission he was pale, dehydrated. and severely acidotic (pH in blood 6.98. plasma H C 0 , - 3.3 mmol/liter). Serum electrolytes ...
We chose this route of administration to reduce animal attrition due to tissue necrosis associated with chronic intraperitoneal injections68, and/or FLX-induced constipation69. The concentration of FLX in the water was selected based on previous work showing that this measure induces an antidepressant-...
According to some, it raises the same concerns as it does in people with chronic non-malignant pain [5]. Chronic opioid use is also associated with chronic constipation, mental clouding, hypogonadism, effects on sexual desire and fertility, sleep disorders, hyperalgesia, and tolerance, misuse ...
sore muscles, fatigue, poor attention or concentration, skin problems, sensory symptoms (pins and needles, tingling or burning sensation), hearing impairment, constipation, stomach pain, headache, breathing difficulties, palpitations, dizziness, chest pain, cough, diarrhea, anosmia, and other symptoms....
Background and aims Depression is common in older adults with persistent pain. Cognitive-behavioural models of pain propose that the relationship between pain and depression is influenced or mediated by interpretations of events (cognitions), rather than
The primary outcome was incidence of persistent GI symptoms (diarrhea, abdominal pain, bloating, constipation, fecal incontinence, nausea, vomiting) after resolution of GI-irAE. Hazard ratios evaluated the association between parameters and time to persistent GI symptoms.#One hundred four patients with...
Adverse events included transient mild to moderate constipation (10 participants [33%]), transient worsening of flushing (4 participants [13%]), bloating (3 participants [10%]), and upper respiratory tract infections (3 participants [10%]), consistent with previous ...
Bladder wall injection of Botulinum toxin has been linked to life-threatening adverse effects on tissues at a distance from the injection site, following its diffusion throughout the body. Muscle weakness, asthenia and constipation have been reported [7]. Cho and Kim [5] also stated that the ...