the bile acid intermediates di- and trihydroxycholestanoic acid which cannot be oxidized in mitochondria. Furthermore, peroxisomes catalyze the synthesis of a particular type of lipids, i.e. ether-linked phospholipids, which are highly abundant in brain, especially in myelin. The current state of ...
Although physical interactions between both organelles had been identified in mammalian cells84,137, a co-regulation at the organismal level—especially in the context of aging—was not known. Our screen identifies upstream key regulators of this lipid droplet–peroxisome network as well as genes ...
Mitochondria and peroxisomes are two types of functionally close-related organelles, and both play essential roles in lipid and ROS metabolism. However, how they physically interact with each other is not well understood. In this study, we apply the prox
All analysed proteins were less abundant in pancreas compared to the liver (especially catalase, ACOX1 and PEX14) (Fig. 1). Noteworthy is that ABCD3 in the pancreas presents different molecular weights than in the liver (Fig. 1). In the liver, ACOX1 displays two protein bands on the ...
Since 1986, all peroxisome isolation procedures have been performed on fresh organs (especially rat liver) [26,27,28,30]. In this protocol, we isolated peroxisomes from frozen rat liver for the first time. Our protocol for isolation and purification of peroxisomes from the frozen liver was ...