Peroxisomal acyl-coenzyme A oxidase is a rate-limiting en- zyme in a very-long-chain fatty acid beta-oxidation system. Biochem Biophys Res Commun 1994; 201: 1541-1547 [PMID: 8024599 DOI: 10.1006/bbrc.1994.1879]Aoyama T, Souri M, Kamijo T, Ushikubo S and Hashimoto T ( 1994) Peroxisomal...
The peroxisomal acyl-CoA oxidase has been purified from extracts of the yeast Candida tropicalis grown with alkanes as the principal energy source. The enzyme has a molecular weight of 552,000 and a subunit molecular weight of 72,100. Using an experimentally determined molar extinction coefficient ...
英文别名: ACOX2 (Acyl-Coenzyme A Oxidase 2, Branched Chain, BCOX, BRCACOX, BRCOX, THCCox, Peroxisomal Branched Chain Acyl-CoA Oxidase, THCA-CoA Oxidase, Trihydroxycoprostanoyl-CoA Oxidase) (AP) 中文名: 中文别名: CBNumber: CB04969749 分子式: 分子量: 0 MOL File: Mol file 化学...
A simple spectrophotometric assay was developed for peroxisomal fatty acyl-CoA oxidase activity. The assay, based on the H2O2-dependent oxidation of leuco-... GM Small,K Burdett,MJ Connock - 《Biochemical Journal》 被引量: 524发表: 1985年 Identification of the peroxisomal β-oxidation enzymes inv...
The biologic role of peroxisomal β-oxidation system, which consists of three enzymes: fatty acyl-CoA oxidase (ACOX), enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase (HD), and thiolase, has been examined in mice by disrupting ACOX gene, which encodes the first and rate-limiting enzyme of...
neonatal adrenoleukodystrophy; IRD, infantile Refsum disease; AOXD, acyl-CoA oxidase 1 deficiency; DBPD, D-bifunctional protein deficiency; RCDP, rhizomelic chondrodysplasia punctata; X-ALD, X-linked adrenoleukodystrophy; RD, Refsum disease; AMACRD, 2-methylacyl-CoA racemase deficiency; N, normal;...
Using complementation analysis, 24 were found to be deficient in enoylcoenzyme A hydratase/3-hydroxyacylcoenzyme A dehydrogenase bifunctional enzyme and 5 were deficient in acyl-CoA oxidase. Elevated plasma very long-chain fatty acids (VLCFA), impaired fibroblast VLCFA beta-oxidation, decreased ...
Fatty acyl-CoA oxidase from rat liver was partially purified and characterized as a peroxisomal flavoprotein oxidase. A sedimentation coefficient of 7.7 S was estimated from sucrose gradients and a Stokes radius of 42.3 was deduced from gel-exclusion chromatography. These data allow to estimate a mol...
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ACOX3 acyl-CoA oxidase 3 BAAT bile acid-CoA:amino acid N-acyltransferase CA cholic acid CoASH coenzyme A CDCA chenodeoxycholic acid DMN-CoA dimethylnonanoyl-CoA FAAH fatty acid amide hydrolase FXR farnesoid X receptor HAO1 hydroxyacid oxidase 1 HNF-4α hepatocyte nuclear factor 4 alpha NAT N-...