Peripheral venous disease often arises from venous hypertension due to either venous reflux or proximal venous obstruction. When describing venous disease, it is often helpful to divide the topic into these two broad groups based on underlying pathophysiology. This chapter will describe open and ...
Arterial and venous diseases have been always considered as two completely different entities, but the recent discovery of a relationship between arterial and venous thrombosis have challenged this assumption. ED, considered to be an early process in the pathophysiology of atherosclerotic disease, could ...
Clinical pharmacology, physiology and pathophysiology of superficial veins--1. 1. Venous resistance contributes very little to total peripheral resistance; more than half of the total blood volume, however, is contained in the extrath... WH Aellig - 《British Journal of Clinical Pharmacology》 被...
Peripheral vascular disease (PVD) is a term applicable to several vessel occlusive diseases, whether they stem from the venous system or the arterial system. For the purpose of this chapter, discussion is limited to peripheral atherosclerotic vascular disease, also known as peripheral vascular occlusiv...
of the vascular function curve. Along with the TPR and relative compliances, this determines the vascular function curve. Its point of intersection with the cardiac function curve determines the operating point of the entire system, which is the cardiac output (CO), equal to the venous return....
Purpose : Transpulmonary biomarkers may provide insight into pulmonary hypertension (PH) pathophysiology, but require cardiac catheterization. We investigated whether the peripheral arterial–venous ratio (PR) could substitute for the transpulmonary ratio (TPR). Materials and methods: Blood from the pulmonar...
Emerging insights into the pathophysiology of osteoporosis. N Engl J Med. 1995;332:305–11. Article CAS PubMed Google Scholar Tsukasaki M, Takayanagi H. Osteoimmunology: evolving concepts in bone-immune interactions in health and disease. Nat Rev Immunol. 2019;19:626–42. Article CAS PubMed...
6,7 Venous thromboembolism (VTE) and peripheral vascular disease (PVD) are vascular diseases that are associated with serious systemic effects.8,9 Chronic inflammation is considered the pivotal role in the pathophysiology of VTE and PVD.10,11 As psoriasis shares similar inflammatory pathomechanisms ...
In short; for NTR, venous blood samples were drawn between 0700-1100 after an overnight fast and usually in the subjects’ homes. Within 20 minutes of sampling, heparinized whole blood was transferred into PAXgene Blood RNA tubes (Qiagen) and stored at -20°C. The PAXgene tubes were ...
Among CCR interactions, chemokines are best known for their ability to stimulate the migration of leukocytes (e.g. PBMCs) and chemokines in particular are known to play an important role in the pathophysiology of cardiovascular disease [26]. Chemokines bind to specific G protein-coupled receptors...