Neuropathic pain, ie, pain arising directly from a lesion or disease affecting the somatosensory afferent pathway, manifests with various symptoms, the commonest being ongoing burning pain, electrical shock-like sensations, and dynamic mechanical allodynia. Reliable insights into th...
Rapid acting pain control for onset of sharp, unpredictable flares for neuropathic pain Disease overview Definition and symptoms An essential element of neuropathic pain is the combination of sensory loss with hypersensitivity in the painful area.1 The nerves in the extremities (hands, arms, feet...
Peripheral Neuropathy Symptoms With peripheral neuropathy, sufferers report moderate to severe pain and/or a numbing and/or tingling sensations, especially in the feet and hands. As the condition worsens, very sharp shooting pains can become common. People with this painful condition often complain ...
Causes of Peripheral Neuropathy There are a number of different causes of peripheral neuropathy. The way in which the nerve is damaged may vary with each cause thereby contributing to different symptoms. It includes autoimmune disorders, infections, inherited disorders, metabolic diseases, nutritional de...
Why Do Our Neuropathy Pain Relief Programs Work? We Treat the Nerves! Learn More About Peripheral Neuropathy →Peripheral Neuropathy Causes There are many different factors that could trigger peripheral nerve damage and lead to neuropathic pain symptoms. Here are some common causes of peripheral ...
symptoms, and barriers associated with CIPNs. Following important research from the fields of pain, behavior and psychoneuroimmunology (PNI), we suggest that injury to peripheral nerves after chemotherapeutic treatments initiates immune to brain communication, which further modulates the biological mechanisms...
Patients with peripheral neuropathy frequently suffer from positive sensory (pain and paresthesias) and motor (muscle cramping) symptoms even in the recovery phase of the disease. To investigate the pathophysiology of increased axonal excitability in peripheral nerve regeneration, we assessed the temporal...
High dose of paclitaxel is well reported to induce neuropathy, however, instead of characteristic neuropathic pain symptoms, the hypoesthesia and anesthesia like symptoms such as numbness and paresthesias are observed. It is reported that higher doses of paclitaxel induces axonal degeneration to the ...
They found that TENS therapy significantly improved generally neuropathic pain symptoms in the treatment of symptomatic DPN (ES = − 1.01, 95% CI − 2.01 to − 0.01). The authors concluded that TENS therapy is effective for painful DPN. Yet their results are consistent...
Neuropathic pain in the general population: a systematic review of epidemiological studies. Most patients with neuropathic pain symptoms present and are managed in primary care, with only a minority being referred for specialist clinical assessmen... HO Van,SK Austin,RA Khan,... - 《Pain》 被引...