Concern has been raised about possible human health effects of perfluorooctanoic acid (PFOA) and related compounds, which have been detected in human blood in many locations. Evidence suggests that these compounds are persistent in the environment and human body. Studies of laboratory animals indicate...
Human exposure to perfluorooctanoic acid (PFOA) and other perfluoroalkyl chemicals (PFCs) has raised concern because these chemicals are persistent in the environment, bioaccumulated, and biomagnified along food chains and have been shown to cause developmental and other adverse health effects in laborat...
A. Epidemiologic evidence on the health effects of perfluorooctanoic acid (PFOA). Environ. Health Perspect. 118, 1100–1108 (2010). 10. Nelson, J. W., Hatch, E. E. & Webster, T. F. Exposure to polyfluoroalkyl chemicals and cholesterol, body weight, and insulin resistance in the ...
Data on the human health effects of PFOA are sparse. There is relatively consistent evidence of modest positive associations with cholesterol and uric acid, although the magnitude of the cholesterol effect is inconsistent across different exposure levels. There is some but much less consistent evidence...
Perfluorooctanoic acid (PFOA) is an environmentally persistent chemical that poses significant risks to human health. Studies have shown that PFOA affects female reproduction, but the specific impact on endometrial receptivity and the underlying mechanisms remain poorly understood. In this study, we invest...
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Perfluorooctanoic acid (PFOA) has been widely documented to affect various aspects of health, including development, metabolism and neuronal function in a variety of organisms. Despite numerous reports detailing these effects, a comprehensive mechanistic model remains elusive, especially with regard to the...
Recently, perfluorooctanoic acid (PFOA) has become a significant issue in many aspects of environmental ecology, toxicology, pathology and life sciences because it may have serious effects on the endocrine, immune and nervous systems and can lead to embryonic deformities and other diseases. Human seru...
Perfluorooctanoic acid (PFOA) and related chemicals among the per- and polyfluoroalkyl substances are widely distributed in the environment. Adverse health effects may occur even at low exposure levels. A large-scale contamination of drinking water resources, especially the rivers Mhne and Ruhr, was...
Perfluorooctanoic acid (PFOA) has received an increasing attention in the agricultural and food industries due to its risk to human health. To facilitate the development of novel biomarkers of Escherichia coli against PFOA through multi-omics technologies, and to reveal the resistance mechanism of E....