Regional plots of the four newly identified loci that reached genome-wide significant association with body fat percentage in all-ancestry analyses, in men and women combined for the COBLL1/GRB14 and IGF2BP1 loci (a,b), and separately for the CRTC1 and PLA2G6 (c,d). Each symbol ...
Of the 12 loci, four showed significant sex-specific effects. For the loci nearIRS1andPLA2G6,the effect in men was twice as large as in women, whereas for theTMEM18andCRTC1loci the effect was two- to threefold larger in women than in men (Table 1). As the European-ancestry-only po...